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Erschienen in: International Journal of Hematology 5/2015

01.11.2015 | Case Report

Imatinib-induced gastric antral vascular ectasia in three patients with chronic myeloid leukaemia

verfasst von: Jeremy Ong, David Yeung, Robin Filshie, Timothy P. Hughes, Harshal Nandurkar

Erschienen in: International Journal of Hematology | Ausgabe 5/2015

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Abstract

Imatinib is generally well tolerated, but gastric antral vascular ectasia (GAVE) remains a rare but significant complication of imatinib therapy. Whilst this complication has been described in other disease settings, only one other case of GAVE has been reported in a chronic myeloid leukaemia (CML) patient receiving imatinib. Herein, we present three CML patients with GAVE complicating imatinib therapy. In all cases, GAVE resolved only with cessation of imatinib. This confirms a causal relationship between GAVE and imatinib. GAVE should be considered as a possible cause of anaemia and upper gastrointestinal bleeding in patients receiving imatinib therapy.
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Metadaten
Titel
Imatinib-induced gastric antral vascular ectasia in three patients with chronic myeloid leukaemia
verfasst von
Jeremy Ong
David Yeung
Robin Filshie
Timothy P. Hughes
Harshal Nandurkar
Publikationsdatum
01.11.2015
Verlag
Springer Japan
Erschienen in
International Journal of Hematology / Ausgabe 5/2015
Print ISSN: 0925-5710
Elektronische ISSN: 1865-3774
DOI
https://doi.org/10.1007/s12185-015-1824-y

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