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Heavy ion-related bystander effects

  • COSMIC RADIATION: Sino-Italian Cooperation
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Abstract

Space radiation is composed of high-energy protons and heavier charged particles, which is distinct from common terrestrial forms of radiation. These particles can damage both shielding materials and biological systems. Although the fluence of space radiation is typically low, the effects are cumulative and may pose great risk during human exploration beyond low Earth orbit. In recent years, radiation-induced non-targeted effects, in which extranuclear and extracellular events may also contribute to the biological consequences of exposure to low doses of radiation, have been demonstrated to increase the detrimental effects caused by radiation in some in vitro and in vivo systems. Here, studies on non-targeted effects caused by radiation are summarized, with special emphasis on heavy ion-related bystander effects and cytoplasmic irradiation-induced effects.

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Correspondence to Mei Hong.

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Hong, M. Heavy ion-related bystander effects. Rend. Fis. Acc. Lincei 25 (Suppl 1), 65–68 (2014). https://doi.org/10.1007/s12210-013-0285-6

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  • DOI: https://doi.org/10.1007/s12210-013-0285-6

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