nach oben

Journal of Cardiovascular Translational Research

Erschienen in:

17.01.2017 | Original Article

Intravascular Ultrasound Characterization of a Tissue-Engineered Vascular Graft in an Ovine Model

verfasst von: Victoria K. Pepper, Elizabeth S. Clark, Cameron A. Best, Ekene A. Onwuka, Tadahisa Sugiura, Eric D. Heuer, Lilamarie E. Moko, Shinka Miyamoto, Hideki Miyachi, Darren P. Berman, Sharon L. Cheatham, Joanne L. Chisolm, Toshiharu Shinoka, Christopher K. Breuer, John P. Cheatham

Erschienen in: Journal of Cardiovascular Translational Research | Ausgabe 2/2017

Einloggen, um Zugang zu erhalten

Abstract

Patients who undergo implantation of a tissue-engineered vascular graft (TEVG) for congenital cardiac anomalies are monitored with echocardiography, followed by magnetic resonance imaging or angiography when indicated. While these methods provide data regarding the lumen, minimal information regarding neotissue formation is obtained. Intravascular ultrasound (IVUS) has previously been used in a variety of conditions to evaluate the vessel wall. The purpose of this study was to evaluate the utility of IVUS for evaluation of TEVGs in our ovine model. Eight sheep underwent implantation of TEVGs either unseeded or seeded with bone marrow-derived mononuclear cells. Angiography, IVUS, and histology were directly compared. Endothelium, tunica media, and graft were identifiable on IVUS and histology at multiple time points. There was strong agreement between IVUS and angiography for evaluation of luminal diameter. IVUS offers a valuable tool to evaluate the changes within TEVGs, and clinical translation of this application is warranted.

Hoffman, J. I., & Kaplan, S. (2002). The incidence of congenital heart disease. Journal of the American College of Cardiology, 39(12), 1890–1900.CrossRefPubMed

Simeone, R. M., Oster, M. E., Cassell, C. H., Armour, B. S., Gray, D. T., & Honein, M. A. (2014). Pediatric inpatient hospital resource use for congenital heart defects. Birth Defects Research. Part A, Clinical and Molecular Teratology, 100(12), 934–943. doi:10.1002/bdra.23262.CrossRefPubMedPubMedCentral

Russo, C. A, Elixhauser, A. (2006). Hospitalizations for Birth Defects, 2004: Statistical Brief #24. In: Healthcare Cost and Utilization Project (HCUP) Statistical Briefs. Rockville (MD).

Shin’oka, T., Matsumura, G., Hibino, N., Naito, Y., Watanabe, M., Konuma, T., Sakamoto, T., Nagatsu, M., & Kurosawa, H. (2005). Midterm clinical result of tissue-engineered vascular autografts seeded with autologous bone marrow cells. Journal of Thoracic and Cardiovascular Surgery, 129(6), 1330–1338. doi:10.1016/j.jtcvs.2004.12.047.CrossRefPubMed

Hibino, N., McGillicuddy, E., Matsumura, G., Ichihara, Y., Naito, Y., Breuer, C., & Shinoka, T. (2010). Late-term results of tissue-engineered vascular grafts in humans. Journal of Thoracic and Cardiovascular Surgery, 139(2), 431–436. doi:10.1016/j.jtcvs.2009.09.057. 436 e431-432.CrossRefPubMed

Pedra, C. A. C., Fleishman, C., Pedra, S. F., & Cheatham, J. P. (2011). New imaging modalities in the catheterization laboratory. Current Opinion in Cardiology, 26(2), 86–93. doi:10.1097/HCO.0b013e3283437fb4.CrossRefPubMed

Diethrich, E. B., Irshad, K., & Reid, D. B. (2006). Virtual histology and color flow intravascular ultrasound in peripheral interventions. Seminars in Vascular Surgery, 19(3), 155–162. doi:10.1053/j.semvascsurg.2006.06.001.CrossRefPubMed

Lee, J. T., Fang, T. D., & White, R. A. (2006). Applications of intravascular ultrasound in the treatment of peripheral occlusive disease. Seminars in Vascular Surgery, 19(3), 139–144. doi:10.1053/j.semvascsurg.2006.06.004.CrossRefPubMed

Pearce, B. J., & Jordan, W. D., Jr. (2009). Using IVUS during EVAR and TEVAR: improving patient outcomes. Seminars in Vascular Surgery, 22(3), 172–180. doi:10.1053/j.semvascsurg.2009.07.009.CrossRefPubMed

10.

Wallace, G. A., Starnes, B. W., Hatsukami, T. S., Sobel, M., Singh, N., & Tran, N. T. (2015). Intravascular ultrasound is a critical tool for accurate endograft sizing in the management of blunt thoracic aortic injury. Journal of Vascular Surgery, 61(3), 630–635. doi:10.1016/j.jvs.2014.10.014.CrossRefPubMed

11.

Marrocco, C. J., Jaber, R., White, R. A., Walot, I., DeVirgilio, C., Donayre, C. E., & Kopchok, G. (2012). Intravascular ultrasound. Seminars in Vascular Surgery, 25(3), 144–152. doi:10.1053/j.semvascsurg.2012.07.006.CrossRefPubMed

12.

Park, S. J., Kang, S. J., Virmani, R., Nakano, M., & Ueda, Y. (2012). In-stent neoatherosclerosis: a final common pathway of late stent failure. Journal of the American College of Cardiology, 59(23), 2051–2057. doi:10.1016/j.jacc.2011.10.909.CrossRefPubMed

13.

Gogas, B. D., Farooq, V., Serruys, P. W., & Garcia-Garcia, H. M. (2011). Assessment of coronary atherosclerosis by IVUS and IVUS-based imaging modalities: progression and regression studies, tissue composition and beyond. The International Journal of Cardiovascular Imaging, 27(2), 225–237. doi:10.1007/s10554-010-9791-0.CrossRefPubMedPubMedCentral

14.

Nasu, K., Tsuchikane, E., Katoh, O., Vince, D. G., Margolis, P. M., Virmani, R., Surmely, J. F., Ehara, M., Kinoshita, Y., Fujita, H., Kimura, M., Asakura, K., Asakura, Y., Matsubara, T., Terashima, M., & Suzuki, T. (2008). Impact of intramural thrombus in coronary arteries on the accuracy of tissue characterization by in vivo intravascular ultrasound radiofrequency data analysis. American Journal of Cardiology, 101(8), 1079–1083. doi:10.1016/j.amjcard.2007.11.064.CrossRefPubMed

15.

Nair, A., Margolis, M. P., Kuban, B. D., & Vince, D. G. (2007). Automated coronary plaque characterisation with intravascular ultrasound backscatter: ex vivo validation. EuroIntervention, 3(1), 113–120.PubMed

16.

Nair, A., Kuban, B. D., Tuzcu, E. M., Schoenhagen, P., Nissen, S. E., & Vince, D. G. (2002). Coronary plaque classification with intravascular ultrasound radiofrequency data analysis. Circulation, 106(17), 2200–2206.CrossRefPubMed

17.

Garcia-Garcia, H. M., Gogas, B. D., Serruys, P. W., & Bruining, N. (2011). IVUS-based imaging modalities for tissue characterization: similarities and differences. The International Journal of Cardiovascular Imaging, 27(2), 215–224. doi:10.1007/s10554-010-9789-7.CrossRefPubMedPubMedCentral

18.

Madssen, E., Moholdt, T., Videm, V., Wisloff, U., Hegbom, K., & Wiseth, R. (2014). Coronary atheroma regression and plaque characteristics assessed by grayscale and radiofrequency intravascular ultrasound after aerobic exercise. The American Journal of Cardiology, 114(10), 1504–1511. doi:10.1016/j.amjcard.2014.08.012.CrossRefPubMed

19.

Virmani, R., Kolodgie, F. D., Burke, A. P., Farb, A., & Schwartz, S. M. (2000). Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arteriosclerosis, Thrombosis, and Vascular Biology, 20(5), 1262–1275.CrossRefPubMed

20.

Stone, G. W., Maehara, A., Lansky, A. J., de Bruyne, B., Cristea, E., Mintz, G. S., Mehran, R., McPherson, J., Farhat, N., Marso, S. P., Parise, H., Templin, B., White, R., Zhang, Z., Serruys, P. W., & Investigators, P. (2011). A prospective natural-history study of coronary atherosclerosis. New England Journal of Medicine, 364(3), 226–235. doi:10.1056/NEJMoa1002358.CrossRefPubMed

21.

Fatakdawala, H., Gorpas, D., Bishop, J. W., Bec, J., Ma, D., Southard, J. A., Margulies, K. B., & Marcu, L. (2015). Fluorescence lifetime imaging combined with conventional intravascular ultrasound for enhanced assessment of atherosclerotic plaques: an ex vivo study in human coronary arteries. Journal of Cardiovascular Translational Research, 8(4), 253–263. doi:10.1007/s12265-015-9627-3.CrossRefPubMedPubMedCentral

22.

Ishii, M., Kato, H., Kawano, T., Akagi, T., Maeno, Y., Sugimura, T., Hashino, K., & Takagishi, T. (1995). Evaluation of pulmonary artery histopathologic findings in congenital heart disease: an in vitro study using intravascular ultrasound imaging. Journal of the American College of Cardiology, 26(1), 272–276.CrossRefPubMed

23.

Xu, J., Shiota, T., Omoto, R., Zhou, X., Kyo, S., Ishii, M., Rice, M. J., & Sahn, D. J. (1997). Intravascular ultrasound assessment of regional aortic wall stiffness, distensibility, and compliance in patients with coarctation of the aorta. American Heart Journal, 134(1), 93–98.CrossRefPubMed

24.

Day, R. W., & Tani, L. Y. (1997). Pulmonary intravascular ultrasound in infants and children with congenital heart disease. Catheterization and Cardiovascular Diagnosis, 41(4), 395–398.CrossRefPubMed

25.

Berger, R. M., Cromme-Dijkhuis, A. H., Hop, W. C., Kruit, M. N., & Hess, J. (2002). Pulmonary arterial wall distensibility assessed by intravascular ultrasound in children with congenital heart disease: an indicator for pulmonary vascular disease? Chest, 122(2), 549–557.CrossRefPubMed

26.

Veeram Reddy, S. R., Welch, T. R., Wang, J., Richardson, J. A., Forbess, J. M., Riegel, M., & Nugent, A. W. (2015). A novel design biodegradable stent for use in congenital heart disease: mid-term results in rabbit descending aorta. Catheterization and Cardiovascular Interventions, 85(4), 629–639. doi:10.1002/ccd.25648.CrossRefPubMed

27.

Hibino, N., Nalbandian, A., Devine, L., Martinez, R. S., McGillicuddy, E., Yi, T., Karandish, S., Ortolano, G. A., Shin’oka, T., Snyder, E., & Breuer, C. K. (2011). Comparison of human bone marrow mononuclear cell isolation methods for creating tissue-engineered vascular grafts: novel filter system versus traditional density centrifugation method. Tissue Engineering. Part C, Methods, 17(10), 993–998. doi:10.1089/ten.TEC.2011.0110.CrossRefPubMedPubMedCentral

28.

Hibino, N., Yi, T., Duncan, D. R., Rathore, A., Dean, E., Naito, Y., Dardik, A., Kyriakides, T., Madri, J., Pober, J. S., Shinoka, T., & Breuer, C. K. (2011). A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts. FASEB Journal, 25(12), 4253–4263. doi:10.1096/fj.11-186585.CrossRefPubMedPubMedCentral

29.

Khosravi, R., Miller, K. S., Best, C. A., Shih, Y. C., Lee, Y. U., Yi, T., Shinoka, T., Breuer, C. K., & Humphrey, J. D. (2015). Biomechanical diversity despite mechanobiological stability in tissue engineered vascular grafts 2 years post-implantation. Tissue Engineering Part A, 21(9–10), 1529–1538. doi:10.1089/ten.tea.2014.0524.CrossRefPubMedPubMedCentral

30.

van Ditzhuijzen, N. S., van den Heuvel, M., Sorop, O., van Duin, R. W., Krabbendam-Peters, I., van Haeren, R., Ligthart, J. M., Witberg, K. T., Duncker, D. J., Regar, E., van Beusekom, H. M., & van der Giessen, W. J. (2011). Invasive coronary imaging in animal models of atherosclerosis. Netherlands Heart Journal, 19(10), 442–446. doi:10.1007/s12471-011-0187-0.CrossRefPubMedPubMedCentral

Titel: Intravascular Ultrasound Characterization of a Tissue-Engineered Vascular Graft in an Ovine Model
verfasst von: Victoria K. Pepper
Elizabeth S. Clark
Cameron A. Best
Ekene A. Onwuka
Tadahisa Sugiura
Eric D. Heuer
Lilamarie E. Moko
Shinka Miyamoto
Hideki Miyachi
Darren P. Berman
Sharon L. Cheatham
Joanne L. Chisolm
Toshiharu Shinoka
Christopher K. Breuer
John P. Cheatham
Publikationsdatum: 17.01.2017
Verlag: Springer US
Erschienen in: Journal of Cardiovascular Translational Research / Ausgabe 2/2017
Print ISSN: 1937-5387
Elektronische ISSN: 1937-5395
DOI: https://doi.org/10.1007/s12265-016-9725-x

Neu im Fachgebiet Kardiologie

19.04.2024 | Vorhofflimmern | Nachrichten

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Intravascular Ultrasound Characterization of a Tissue-Engineered Vascular Graft in an Ovine Model

Abstract

Neu im Fachgebiet Kardiologie

Parodontalbehandlung verbessert Prognose bei Katheterablation

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Sind Betablocker auch für ältere herzschwache Personen nützlich?

Stillende Frauen haben geringeres kardiovaskuläres Risiko

Update Kardiologie

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 2/2017

Tissue Engineering—Bridging the Gap

Stem Cell Spheroids and Ex Vivo Niche Modeling: Rationalization and Scaling-Up

Decellularized Cryopreserved Allografts as Off-the-Shelf Allogeneic Alternative for Heart Valve Replacement: In Vitro Assessment Before Clinical Translation

The Dynamics of Cardiovascular Biomarkers in non-Elite Marathon Runners

Fixation of Bovine Pericardium-Based Tissue Biomaterial with Irreversible Chemistry Improves Biochemical and Biomechanical Properties

Utilizing the Foreign Body Response to Grow Tissue Engineered Blood Vessels in Vivo

Neu im Fachgebiet Kardiologie

Parodontalbehandlung verbessert Prognose bei Katheterablation

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Sind Betablocker auch für ältere herzschwache Personen nützlich?

Stillende Frauen haben geringeres kardiovaskuläres Risiko

Update Kardiologie