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Hemolytic Disease of the Newborn Due to Anti-c Isoimmunization: A Case Report

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Abstract

The Rhesus (Rh) blood group is one of the most complex blood groups known in humans. It has remained of primary importance in obstetrics, being the main cause of hemolytic disease of the newborn (HDN). Anti-D causes the most severe form of HDN. Other Rh allo antibodies that are capable of causing severe HDN include anti-c, which clinically is the most important Rh antigen after the D antigen. We report a case of hemolytic disease of the newborn due to Rh anti-c in an infant of an Rh positive mother.

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References

  1. Chavez GF, Mulinare J, Edmonds LD (1991) Epidemiology of Rh hemolytic disease of the newborn in the United States. JAMA 265(24):4–3270

    Article  Google Scholar 

  2. Dean L (2006) The Rh blood group. In: Blood groups and red cell antigens. National library of medicine (US), NCBI, Bethesda

  3. Sana A, Safae H, Chekabab H, Abdelhak B, Moustapha H (2009) Hemolytic disease of the newborn due to anti-c. BMJ Case Rep. doi:10.1136/bcr:09.2008.0987

  4. Geoff D, Imelda B (2007) The Rh blood group system. In: Essential guide to blood groups. Blackwell Publishing, Amsterdam, pp 33–44

  5. Singla S, Kumar S, Kumar RK, Sharma JB, Kachhawa G (2010) Severe hydrops in the infant of a Rhesus D positive mother due to anti-c antibodies diagnosed antenatally: a case report. J Case Rep 4:57

    Article  Google Scholar 

  6. Avent ND, Reid ME (2000) The Rh blood group system: a review. Blood 95:87–375

    Google Scholar 

  7. Koelewijn J, Schoot V, Vrijkotte CE, de Bonsel GJ, Haas M (2008) Effect of screening for red cell antibodies, other than anti-D, to detect hemolytic disease of the fetus and newborn: a population study in The Netherlands. Obstet Gynecol Surv 63:64–563

    Article  Google Scholar 

  8. Hackney DN, Knudtson EJ, Rossi KQ, Krugh D, O’Shaughnessy RD (2004) Management of pregnancies complicated by anti-c. Obstet Gynecol 103:24–30

    Article  PubMed  CAS  Google Scholar 

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Acknowledgments

The authors would like to thank Dr C K Ganesh, Blood bank officer, JSS Hospital, Mysore.

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Authors and Affiliations

  1. Department of Pathology and Pediatrics, JSS Medical College, JSS University, Mysore, Karnataka, India

    C. S. Sheeladevi, S. Suchitha, G. V. Manjunath & Srinivas Murthy

  2. #367, Adarsha, 6th cross, TK layout, Kuvempunagar, Mysore, 570009, Karnataka, India

    C. S. Sheeladevi

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  1. C. S. Sheeladevi
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  2. S. Suchitha
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  3. G. V. Manjunath
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  4. Srinivas Murthy
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Correspondence to C. S. Sheeladevi.

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Sheeladevi, C.S., Suchitha, S., Manjunath, G.V. et al. Hemolytic Disease of the Newborn Due to Anti-c Isoimmunization: A Case Report. Indian J Hematol Blood Transfus 29, 155–157 (2013). https://doi.org/10.1007/s12288-012-0159-6

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  • DOI: https://doi.org/10.1007/s12288-012-0159-6

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