Excerpt

Fluorine-18 fluorodeoxyglucose (¹⁸FDG) positron emission tomography (PET) imaging is growing as a standard diagnostic tool in patients with cardiac sarcoidosis (CS)1 and is an emerging imaging modality in other challenging patient populations including those with myocarditis,2 neoplastic cardiac disease,3 and cardiac allograft rejection.4 Ultimately, widespread implementation and clinical utilization of ¹⁸FDG PET imaging for these indications is predicated upon both optimization and standardization of patient preparation protocols.5 As a result, ¹⁸FDG PET protocol optimization has been an active area of research, with recent publications in the Journal of Nuclear Cardiology focusing on preparations to suppress physiologic myocardial glucose uptake. In a recent publication in the journal, Manabe et al.6 assessed combined prolonged fasting, low-carbohydrate diet, and heparin administration, whereas in the current issue of the journal, Nensa and colleagues examined the efficacy of a ≥24-hour high-fat, low-carbohydrate, protein-permitted (HFLCPP) diet combined with heparin administration. …