Skip to main content
Erschienen in: International Journal of Behavioral Medicine 5/2018

15.03.2018

Sleepless from the Get Go: Sleep Problems Prior to Initiating Cancer Treatment

verfasst von: Eric S. Zhou, Karen Clark, Christopher J. Recklitis, Richard Obenchain, Matthew Loscalzo

Erschienen in: International Journal of Behavioral Medicine | Ausgabe 5/2018

Einloggen, um Zugang zu erhalten

Abstract

Purpose

Cancer patients are likely to experience sleep problems. Understanding their perception of sleep problems is important as subjective symptom experience is associated with treatment-seeking behavior. We explored the prevalence of sleep problems and its correlates in a large sample of cancer patients at an important but understudied stage of their cancer journey: prior to initiating treatment.

Methods

Cancer patients (5702) (67.5% female; 76.9% White; 23.0% Hispanic), following diagnosis and prior to initiating cancer treatment, completed an electronic screening instrument. Patients across eight different cancer diagnoses (breast, gastrointestinal, gynecological, head and neck, hematological, lung, prostate, urinary) rated their sleep problems on a five-point scale, with those reporting “severe” or “very severe” sleep problems classified as having high sleep problems.

Results

Overall, 12.5% of patients reported high sleep problems. Across diagnoses, the proportion of patients reporting high sleep problems ranged from 4.3 to 13.8%, with prostate cancer patients least likely and gastrointestinal cancer patients most likely to report high sleep problems. Older age, having a partner, higher education, and higher household income were associated with a lower likelihood of experiencing sleep problems. Being female, Black, Hispanic, and reporting anxiety or depression was associated with an increased likelihood of sleep problems.

Conclusions

A sizeable proportion of cancer patients experience significant problems with their sleep before any treatment has occurred. This clinical issue cannot be ignored as treatment is likely to worsen existing sleep problems. Oncology providers should routinely screen for sleep-related problems. Identifying and treating patients for sleep problems during a vulnerable period early in their cancer trajectory should be an essential component of clinical care.
Literatur
2.
Zurück zum Zitat van't Spijker A, Trijsburg RW, Duivenvoorden HJ. Psychological sequelae of cancer diagnosis: a meta-analytical review of 58 studies after 1980. Psychosom Med. 1997;59(3):280–93.CrossRefPubMed van't Spijker A, Trijsburg RW, Duivenvoorden HJ. Psychological sequelae of cancer diagnosis: a meta-analytical review of 58 studies after 1980. Psychosom Med. 1997;59(3):280–93.CrossRefPubMed
3.
Zurück zum Zitat Carter BJ. Long-term survivors of breast cancer. A qualitative descriptive study. Cancer Nurs. 1993;16(5):354–61.CrossRefPubMed Carter BJ. Long-term survivors of breast cancer. A qualitative descriptive study. Cancer Nurs. 1993;16(5):354–61.CrossRefPubMed
4.
Zurück zum Zitat Cimprich B. Pretreatment symptom distress in women newly diagnosed with breast cancer. Cancer Nurs. 1999;22(3):185–94.CrossRefPubMed Cimprich B. Pretreatment symptom distress in women newly diagnosed with breast cancer. Cancer Nurs. 1999;22(3):185–94.CrossRefPubMed
5.
Zurück zum Zitat Dickerson SS, Alqaissi N, Underhill M, Lally RM. Surviving the wait: defining support while awaiting breast cancer surgery. J Adv Nurs. 2011;67(7):1468–79.CrossRefPubMed Dickerson SS, Alqaissi N, Underhill M, Lally RM. Surviving the wait: defining support while awaiting breast cancer surgery. J Adv Nurs. 2011;67(7):1468–79.CrossRefPubMed
6.
Zurück zum Zitat Foley DJ, Monjan AA, Brown SL, Simonsick EM, Wallace RB, Blazer DG. Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep. 1995;18(6):425–32.CrossRefPubMed Foley DJ, Monjan AA, Brown SL, Simonsick EM, Wallace RB, Blazer DG. Sleep complaints among elderly persons: an epidemiologic study of three communities. Sleep. 1995;18(6):425–32.CrossRefPubMed
7.
Zurück zum Zitat Arber S, Bote M, Meadows R. Gender and socio-economic patterning of self-reported sleep problems in Britain. Soc Sci Med. 2009;68(2):281–9.CrossRefPubMed Arber S, Bote M, Meadows R. Gender and socio-economic patterning of self-reported sleep problems in Britain. Soc Sci Med. 2009;68(2):281–9.CrossRefPubMed
8.
Zurück zum Zitat Patel NP, Grandner MA, Xie D, Branas CC, Gooneratne N. “Sleep disparity” in the population: poor sleep quality is strongly associated with poverty and ethnicity. BMC Public Health. 2010;10:475.CrossRefPubMedPubMedCentral Patel NP, Grandner MA, Xie D, Branas CC, Gooneratne N. “Sleep disparity” in the population: poor sleep quality is strongly associated with poverty and ethnicity. BMC Public Health. 2010;10:475.CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Jean-Louis G, Magai CM, Cohen CI, Zizi F, von Gizycki H, DiPalma J, et al. Ethnic differences in self-reported sleep problems in older adults. Sleep. 2001;24(8):926–33.CrossRefPubMed Jean-Louis G, Magai CM, Cohen CI, Zizi F, von Gizycki H, DiPalma J, et al. Ethnic differences in self-reported sleep problems in older adults. Sleep. 2001;24(8):926–33.CrossRefPubMed
12.
Zurück zum Zitat Stepanski EJ, Walker MS, Schwartzberg LS, Blakely LJ, Ong JC, Houts AC. The relation of trouble sleeping, depressed mood, pain, and fatigue in patients with cancer. J Clin Sleep Med. 2009;5(2):132–6.PubMedPubMedCentral Stepanski EJ, Walker MS, Schwartzberg LS, Blakely LJ, Ong JC, Houts AC. The relation of trouble sleeping, depressed mood, pain, and fatigue in patients with cancer. J Clin Sleep Med. 2009;5(2):132–6.PubMedPubMedCentral
15.
Zurück zum Zitat Trudel-Fitzgerald C, Zhou ES, Poole EM, Zhang X, Michels KB, Eliassen AH, et al. Sleep and survival among women with breast cancer: 30 years of follow-up within the nurses’ health study. Br J Cancer. 2017;116:1239–46.CrossRefPubMedPubMedCentral Trudel-Fitzgerald C, Zhou ES, Poole EM, Zhang X, Michels KB, Eliassen AH, et al. Sleep and survival among women with breast cancer: 30 years of follow-up within the nurses’ health study. Br J Cancer. 2017;116:1239–46.CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Irwin DE, Milsom I, Kopp Z, Abrams P, Group ES. Symptom bother and health care–seeking behavior among individuals with overactive bladder. Eur Urol. 2008;53(5):1029–39.CrossRefPubMed Irwin DE, Milsom I, Kopp Z, Abrams P, Group ES. Symptom bother and health care–seeking behavior among individuals with overactive bladder. Eur Urol. 2008;53(5):1029–39.CrossRefPubMed
23.
Zurück zum Zitat Yu S-Y, Nho J-H. Influence of sleep disturbance and depression on quality of life in ovarian cancer patients during chemotherapy. Asian Oncol Nurs. 2015;15(4):203–10.CrossRef Yu S-Y, Nho J-H. Influence of sleep disturbance and depression on quality of life in ovarian cancer patients during chemotherapy. Asian Oncol Nurs. 2015;15(4):203–10.CrossRef
24.
Zurück zum Zitat Redeker NS, Lev EL, Ruggiero J. Insomnia, fatigue, anxiety, depression, and quality of life of cancer patients undergoing chemotherapy. Sch Inq Nurs Pract. 2000;14(4):275–90. discussion 91-8PubMed Redeker NS, Lev EL, Ruggiero J. Insomnia, fatigue, anxiety, depression, and quality of life of cancer patients undergoing chemotherapy. Sch Inq Nurs Pract. 2000;14(4):275–90. discussion 91-8PubMed
31.
Zurück zum Zitat Davidson JR, MacLean AW, Brundage MD, Schulze K. Sleep disturbance in cancer patients. Soc Sci Med. 2002;54(9):1309–21.CrossRefPubMed Davidson JR, MacLean AW, Brundage MD, Schulze K. Sleep disturbance in cancer patients. Soc Sci Med. 2002;54(9):1309–21.CrossRefPubMed
32.
Zurück zum Zitat Loscalzo M, Clark K, Dillehunt J, Rinehart R, Strowbridge R, Smith D. SupportScreen: a model for improving patient outcomes. J Natl Compr Cancer Netw. 2010;8(4):496–504.CrossRef Loscalzo M, Clark K, Dillehunt J, Rinehart R, Strowbridge R, Smith D. SupportScreen: a model for improving patient outcomes. J Natl Compr Cancer Netw. 2010;8(4):496–504.CrossRef
33.
Zurück zum Zitat Zabora JR, Loscalzo MJ, Weber J, editors. Managing complications in cancer: identifying and responding to the patient’s perspective. Semin Oncol Nurs. 2003;19(2):1–9. Zabora JR, Loscalzo MJ, Weber J, editors. Managing complications in cancer: identifying and responding to the patient’s perspective. Semin Oncol Nurs. 2003;19(2):1–9.
34.
Zurück zum Zitat Loscalzo MJ, Clark KL. Problem-related distress in cancer patients drives requests for help: a prospective study. Oncology. 2007;21(9):1133–8.PubMed Loscalzo MJ, Clark KL. Problem-related distress in cancer patients drives requests for help: a prospective study. Oncology. 2007;21(9):1133–8.PubMed
39.
Zurück zum Zitat Savard J, Savard M-H. Insomnia and cancer: prevalence, nature, and nonpharmacologic treatment. Sleep Med Clin. 2013;8(3):373–87.CrossRef Savard J, Savard M-H. Insomnia and cancer: prevalence, nature, and nonpharmacologic treatment. Sleep Med Clin. 2013;8(3):373–87.CrossRef
41.
Zurück zum Zitat Ohayon MM, Caulet M, Priest RG, Guilleminault C. DSM-IV and ICSD-90 insomnia symptoms and sleep dissatisfaction. Br J Psychiatry. 1997;171(4):382–8.CrossRefPubMed Ohayon MM, Caulet M, Priest RG, Guilleminault C. DSM-IV and ICSD-90 insomnia symptoms and sleep dissatisfaction. Br J Psychiatry. 1997;171(4):382–8.CrossRefPubMed
42.
44.
Zurück zum Zitat Kuehner C. Gender differences in unipolar depression: an update of epidemiological findings and possible explanations. Acta Psychiatr Scand. 2003;108(3):163–74.CrossRefPubMed Kuehner C. Gender differences in unipolar depression: an update of epidemiological findings and possible explanations. Acta Psychiatr Scand. 2003;108(3):163–74.CrossRefPubMed
48.
Zurück zum Zitat Taylor DJ, Lichstein KL, Durrence HH, Reidel BW, Bush AJ. Epidemiology of insomnia, depression, and anxiety. Sleep. 2005;28(11):1457–64.CrossRefPubMed Taylor DJ, Lichstein KL, Durrence HH, Reidel BW, Bush AJ. Epidemiology of insomnia, depression, and anxiety. Sleep. 2005;28(11):1457–64.CrossRefPubMed
50.
Zurück zum Zitat Savard J, Davidson JR, Ivers H, Quesnel C, Rioux D, Dupéré V, et al. The association between nocturnal hot flashes and sleep in breast cancer survivors. J Pain Symptom Manag. 2004;27(6):513–22.CrossRef Savard J, Davidson JR, Ivers H, Quesnel C, Rioux D, Dupéré V, et al. The association between nocturnal hot flashes and sleep in breast cancer survivors. J Pain Symptom Manag. 2004;27(6):513–22.CrossRef
54.
Zurück zum Zitat Hall MH, Matthews KA, Kravitz HM, Gold EB, Buysse DJ, Bromberger JT, et al. Race and financial strain are independent correlates of sleep in midlife women: the SWAN sleep study. Sleep. 2009;32(1):73–82.PubMedPubMedCentral Hall MH, Matthews KA, Kravitz HM, Gold EB, Buysse DJ, Bromberger JT, et al. Race and financial strain are independent correlates of sleep in midlife women: the SWAN sleep study. Sleep. 2009;32(1):73–82.PubMedPubMedCentral
55.
Zurück zum Zitat Karacan I, Thornby JI, Anch M, Holzer CE, Warheit GJ, Schwab JJ, et al. Prevalence of sleep disturbance in a primarily urban Florida county. Soc Sci Med. 1976;10(5):239–44.CrossRefPubMed Karacan I, Thornby JI, Anch M, Holzer CE, Warheit GJ, Schwab JJ, et al. Prevalence of sleep disturbance in a primarily urban Florida county. Soc Sci Med. 1976;10(5):239–44.CrossRefPubMed
56.
Zurück zum Zitat Pigeon WR, Heffner K, Duberstein P, Fiscella K, Moynihan J, Chapman BP. Elevated sleep disturbance among blacks in an urban family medicine practice. J Am Board Fam Pract. 2011;24(2):161–8.CrossRef Pigeon WR, Heffner K, Duberstein P, Fiscella K, Moynihan J, Chapman BP. Elevated sleep disturbance among blacks in an urban family medicine practice. J Am Board Fam Pract. 2011;24(2):161–8.CrossRef
57.
Zurück zum Zitat Gold EB, Sternfeld B, Kelsey JL, Brown C, Mouton C, Reame N, et al. Relation of demographic and lifestyle factors to symptoms in a multi-racial/ethnic population of women 40-55 years of age. Am J Epidemiol. 2000;152(5):463–73.CrossRefPubMed Gold EB, Sternfeld B, Kelsey JL, Brown C, Mouton C, Reame N, et al. Relation of demographic and lifestyle factors to symptoms in a multi-racial/ethnic population of women 40-55 years of age. Am J Epidemiol. 2000;152(5):463–73.CrossRefPubMed
59.
60.
Zurück zum Zitat Morphy H, Dunn KM, Lewis M, Boardman HF, Croft PR. Epidemiology of insomnia: a longitudinal study in a UK population. Sleep. 2007;30(3):274–80.PubMed Morphy H, Dunn KM, Lewis M, Boardman HF, Croft PR. Epidemiology of insomnia: a longitudinal study in a UK population. Sleep. 2007;30(3):274–80.PubMed
61.
Zurück zum Zitat Ohayon MM, Smirne S. Prevalence and consequences of insomnia disorders in the general population of Italy. Sleep Med. 2002;3(2):115–20.CrossRefPubMed Ohayon MM, Smirne S. Prevalence and consequences of insomnia disorders in the general population of Italy. Sleep Med. 2002;3(2):115–20.CrossRefPubMed
62.
Zurück zum Zitat Hohagen F, Kappler C, Schramm E, Riemann D, Weyerer S, Berger M. Sleep onset insomnia, sleep maintaining insomnia and insomnia with early morning awakening—temporal stability of subtypes in a longitudinal study on general practice attenders. Sleep. 1994;17(6):551–4.PubMed Hohagen F, Kappler C, Schramm E, Riemann D, Weyerer S, Berger M. Sleep onset insomnia, sleep maintaining insomnia and insomnia with early morning awakening—temporal stability of subtypes in a longitudinal study on general practice attenders. Sleep. 1994;17(6):551–4.PubMed
63.
Zurück zum Zitat Lavie P. Sleep habits and sleep disturbances in industrial workers in Israel: main findings and some characteristics of workers complaining of excessive daytime sleepiness. Sleep. 1980;4(2):147–58.CrossRef Lavie P. Sleep habits and sleep disturbances in industrial workers in Israel: main findings and some characteristics of workers complaining of excessive daytime sleepiness. Sleep. 1980;4(2):147–58.CrossRef
64.
Zurück zum Zitat Leger D, Guilleminault C, Dreyfus JP, Delahaye C, Paillard M. Prevalence of insomnia in a survey of 12,778 adults in France. J Sleep Res. 2000;9(1):35–42.CrossRefPubMed Leger D, Guilleminault C, Dreyfus JP, Delahaye C, Paillard M. Prevalence of insomnia in a survey of 12,778 adults in France. J Sleep Res. 2000;9(1):35–42.CrossRefPubMed
65.
Zurück zum Zitat Hall M, Buysse DJ, Nowell PD, Nofzinger EA, Houck P, Reynolds CF III, et al. Symptoms of stress and depression as correlates of sleep in primary insomnia. Psychosom Med. 2000;62(2):227–30.CrossRefPubMed Hall M, Buysse DJ, Nowell PD, Nofzinger EA, Houck P, Reynolds CF III, et al. Symptoms of stress and depression as correlates of sleep in primary insomnia. Psychosom Med. 2000;62(2):227–30.CrossRefPubMed
68.
Zurück zum Zitat Cairney J, Arnold R. Social class, health and aging: socioeconomic determinants of self-reported morbidity among the noninstitutionalized elderly in Canada. Can J Public Health. 1995;87(3):199–203. Cairney J, Arnold R. Social class, health and aging: socioeconomic determinants of self-reported morbidity among the noninstitutionalized elderly in Canada. Can J Public Health. 1995;87(3):199–203.
69.
Zurück zum Zitat Sutton DA, Moldofsky H, Badley EM. Insomnia and health problems in Canadians. Sleep. 2001;24(6):665–70.CrossRefPubMed Sutton DA, Moldofsky H, Badley EM. Insomnia and health problems in Canadians. Sleep. 2001;24(6):665–70.CrossRefPubMed
71.
Zurück zum Zitat Johnson EO. Sleep in america: 1999. Results from the National Sleep. Foundations. 1999; Johnson EO. Sleep in america: 1999. Results from the National Sleep. Foundations. 1999;
74.
Zurück zum Zitat National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: survivorship. 2015. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: survivorship. 2015.
Metadaten
Titel
Sleepless from the Get Go: Sleep Problems Prior to Initiating Cancer Treatment
verfasst von
Eric S. Zhou
Karen Clark
Christopher J. Recklitis
Richard Obenchain
Matthew Loscalzo
Publikationsdatum
15.03.2018
Verlag
Springer US
Erschienen in
International Journal of Behavioral Medicine / Ausgabe 5/2018
Print ISSN: 1070-5503
Elektronische ISSN: 1532-7558
DOI
https://doi.org/10.1007/s12529-018-9715-2

Weitere Artikel der Ausgabe 5/2018

International Journal of Behavioral Medicine 5/2018 Zur Ausgabe