Skip to main content
Erschienen in: Journal of Echocardiography 3/2016

07.03.2016 | Review Article

Clinical implications of left atrial function assessed by speckle tracking echocardiography

verfasst von: Satoshi Yuda, Atsuko Muranaka, Tetsuji Miura

Erschienen in: Journal of Echocardiography | Ausgabe 3/2016

Einloggen, um Zugang zu erhalten

Abstract

Left atrial (LA) function has a significant impact on cardiovascular diseases and has been assessed by several noninvasive methods. However, several limitations, including the dependence of image quality, single plane assessment, and time-consuming procedures, have prevented widespread clinical application of the assessment of LA function. Strain imaging using tissue Doppler echocardiography enables quantification of LA function. Recently, two-dimensional speckle tracking echocardiography (2D-STE) has been developed as a noninvasive, simple, and reproducible tool for assessment of LA function in patients with cardiovascular disease. 2D-STE enables detection of early LA dysfunction even before LA morphological changes. LA dysfunction determined by 2D-STE can provide additional prognostic information to conventional echocardiographic parameters in patients with cardiovascular diseases. Hence, 2D-STE appears to be a promising technique for diagnosis and therapeutic decision-making. However, standardization of analysis techniques and software applications of 2D-STE is still lacking. Here, we review recent studies on clinical implications of LA function assessed by 2D-STE and summarize the remaining problems to be solved to improve the clinical utility of this tool.
Literatur
1.
Zurück zum Zitat Hoit BD. Left atrial size and function: role in prognosis. J Am Coll Cardiol. 2014;63:493–505.CrossRefPubMed Hoit BD. Left atrial size and function: role in prognosis. J Am Coll Cardiol. 2014;63:493–505.CrossRefPubMed
2.
Zurück zum Zitat Vieira MJ, Teixeira R, Gonçalves L, et al. Left atrial mechanics: echocardiographic assessment and clinical implications. J Am Soc Echocardiogr. 2014;27:463–78.CrossRefPubMed Vieira MJ, Teixeira R, Gonçalves L, et al. Left atrial mechanics: echocardiographic assessment and clinical implications. J Am Soc Echocardiogr. 2014;27:463–78.CrossRefPubMed
3.
Zurück zum Zitat Mor-Avi V, Lang RM, Badano LP, et al. Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE/EAE consensus statement on methodology and indications endorsed by the Japanese Society of Echocardiography. J Am Soc Echocardiogr. 2011;24:277–313.CrossRefPubMed Mor-Avi V, Lang RM, Badano LP, et al. Current and evolving echocardiographic techniques for the quantitative evaluation of cardiac mechanics: ASE/EAE consensus statement on methodology and indications endorsed by the Japanese Society of Echocardiography. J Am Soc Echocardiogr. 2011;24:277–313.CrossRefPubMed
4.
Zurück zum Zitat Inaba Y, Yuda S, Kobayashi N, et al. Strain rate imaging for noninvasive functional quantification of the left atrium: comparative studies in controls and patients with atrial fibrillation. J Am Soc Echocardiogr. 2005;18:729–36.CrossRefPubMed Inaba Y, Yuda S, Kobayashi N, et al. Strain rate imaging for noninvasive functional quantification of the left atrium: comparative studies in controls and patients with atrial fibrillation. J Am Soc Echocardiogr. 2005;18:729–36.CrossRefPubMed
5.
Zurück zum Zitat Morris DA, Takeuchi M, Krisper M, et al. Normal values and clinical relevance of left atrial myocardial function analysed by speckle-tracking echocardiography: multicentre study. Eur Heart J Cardiovasc Imaging. 2015;16:364–72.CrossRefPubMed Morris DA, Takeuchi M, Krisper M, et al. Normal values and clinical relevance of left atrial myocardial function analysed by speckle-tracking echocardiography: multicentre study. Eur Heart J Cardiovasc Imaging. 2015;16:364–72.CrossRefPubMed
6.
Zurück zum Zitat Wakami K, Ohte N, Asada K, et al. Correlation between left ventricular end-diastolic pressure and peak left atrial wall strain during left ventricular systole. J Am Soc Echocardiogr. 2009;22:847–51.CrossRefPubMed Wakami K, Ohte N, Asada K, et al. Correlation between left ventricular end-diastolic pressure and peak left atrial wall strain during left ventricular systole. J Am Soc Echocardiogr. 2009;22:847–51.CrossRefPubMed
7.
Zurück zum Zitat Kuppahally SS, Akoum N, Burgon NS, et al. Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed-enhancement MRI. Circ Cardiovasc Imaging. 2010;3:231–9.CrossRefPubMed Kuppahally SS, Akoum N, Burgon NS, et al. Left atrial strain and strain rate in patients with paroxysmal and persistent atrial fibrillation: relationship to left atrial structural remodeling detected by delayed-enhancement MRI. Circ Cardiovasc Imaging. 2010;3:231–9.CrossRefPubMed
8.
Zurück zum Zitat Cameli M, Lisi M, Righini FM, et al. Usefulness of atrial deformation analysis to predict left atrial fibrosis and endocardial thickness in patients undergoing mitral valve operations for severe mitral regurgitation secondary to mitral valve prolapse. Am J Cardiol. 2013;111:595–601.CrossRefPubMed Cameli M, Lisi M, Righini FM, et al. Usefulness of atrial deformation analysis to predict left atrial fibrosis and endocardial thickness in patients undergoing mitral valve operations for severe mitral regurgitation secondary to mitral valve prolapse. Am J Cardiol. 2013;111:595–601.CrossRefPubMed
9.
Zurück zum Zitat Hayashi S, Yamada H, Bando M, et al. Optimal analysis of left atrial strain by speckle tracking echocardiography: P-wave versus R-wave trigger. Echocardiography. 2015;32:1241–9.CrossRefPubMed Hayashi S, Yamada H, Bando M, et al. Optimal analysis of left atrial strain by speckle tracking echocardiography: P-wave versus R-wave trigger. Echocardiography. 2015;32:1241–9.CrossRefPubMed
10.
Zurück zum Zitat Motoki H, Dahiya A, Bhargava M, et al. Assessment of left atrial mechanics in patients with atrial fibrillation: comparison between two-dimensional speckle-based strain and velocity vector imaging. J Am Soc Echocardiogr. 2012;25:428–35.CrossRefPubMed Motoki H, Dahiya A, Bhargava M, et al. Assessment of left atrial mechanics in patients with atrial fibrillation: comparison between two-dimensional speckle-based strain and velocity vector imaging. J Am Soc Echocardiogr. 2012;25:428–35.CrossRefPubMed
11.
Zurück zum Zitat Kojima T, Kawasaki M, Tanaka R, et al. Left atrial global and regional function in patients with paroxysmal atrial fibrillation has already been impaired before enlargement of left atrium: velocity vector imaging echocardiography study. Eur Heart J Cardiovasc Imaging. 2012;13:227–34.CrossRefPubMed Kojima T, Kawasaki M, Tanaka R, et al. Left atrial global and regional function in patients with paroxysmal atrial fibrillation has already been impaired before enlargement of left atrium: velocity vector imaging echocardiography study. Eur Heart J Cardiovasc Imaging. 2012;13:227–34.CrossRefPubMed
12.
Zurück zum Zitat Yoon YE, Oh IY, Kim SA, et al. Echocardiographic predictors of progression to persistent or permanent atrial fibrillation in patients with paroxysmal atrial fibrillation (E6P Study). J Am Soc Echocardiogr. 2015;28:709–17.CrossRefPubMed Yoon YE, Oh IY, Kim SA, et al. Echocardiographic predictors of progression to persistent or permanent atrial fibrillation in patients with paroxysmal atrial fibrillation (E6P Study). J Am Soc Echocardiogr. 2015;28:709–17.CrossRefPubMed
13.
Zurück zum Zitat Pagola J, Gonzalez-Alujas T, Flores A, et al. Left atrial strain is a surrogate marker for detection of atrial fibrillation in cryptogenic strokes. Stroke. 2014;45:e164–6.CrossRefPubMed Pagola J, Gonzalez-Alujas T, Flores A, et al. Left atrial strain is a surrogate marker for detection of atrial fibrillation in cryptogenic strokes. Stroke. 2014;45:e164–6.CrossRefPubMed
14.
Zurück zum Zitat Motoki H, Negishi K, Kusunose K, et al. Global left atrial strain in the prediction of sinus rhythm maintenance after catheter ablation for atrial fibrillation. J Am Soc Echocardiogr. 2014;27:1184–92.CrossRefPubMedPubMedCentral Motoki H, Negishi K, Kusunose K, et al. Global left atrial strain in the prediction of sinus rhythm maintenance after catheter ablation for atrial fibrillation. J Am Soc Echocardiogr. 2014;27:1184–92.CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Obokata M, Negishi K, Kurosawa K, et al. Left atrial strain provides incremental value for embolism risk stratification over CHA2DS2-VASc score and indicates prognostic impact in patients with atrial fibrillation. J Am Soc Echocardiogr. 2014;27:709–16.CrossRefPubMed Obokata M, Negishi K, Kurosawa K, et al. Left atrial strain provides incremental value for embolism risk stratification over CHA2DS2-VASc score and indicates prognostic impact in patients with atrial fibrillation. J Am Soc Echocardiogr. 2014;27:709–16.CrossRefPubMed
16.
Zurück zum Zitat Kusunose K, Motoki H, Popovic ZB, et al. Independent association of left atrial function with exercise capacity in patients with preserved ejection fraction. Heart. 2012;98:1311–7.CrossRefPubMed Kusunose K, Motoki H, Popovic ZB, et al. Independent association of left atrial function with exercise capacity in patients with preserved ejection fraction. Heart. 2012;98:1311–7.CrossRefPubMed
17.
Zurück zum Zitat Yang LT, Liu YW, Shih JY, et al. Predictive value of left atrial deformation on prognosis in severe primary mitral regurgitation. J Am Soc Echocardiogr. 2015;28:1309–17.CrossRefPubMed Yang LT, Liu YW, Shih JY, et al. Predictive value of left atrial deformation on prognosis in severe primary mitral regurgitation. J Am Soc Echocardiogr. 2015;28:1309–17.CrossRefPubMed
18.
Zurück zum Zitat Ancona R, Comenale Pinto S, Caso P, et al. Two-dimensional atrial systolic strain imaging predicts atrial fibrillation at 4-year follow-up in asymptomatic rheumatic mitral stenosis. J Am Soc Echocardiogr. 2013;26:270–7.CrossRefPubMed Ancona R, Comenale Pinto S, Caso P, et al. Two-dimensional atrial systolic strain imaging predicts atrial fibrillation at 4-year follow-up in asymptomatic rheumatic mitral stenosis. J Am Soc Echocardiogr. 2013;26:270–7.CrossRefPubMed
19.
Zurück zum Zitat Galli E, Fournet M, Chabanne C, et al. Prognostic value of left atrial reservoir function in patients with severe aortic stenosis: a 2D speckle-tracking echocardiographic study. Eur Heart J Cardiovasc Imaging. 2015. doi:10.1093/ehjci/jev230. Galli E, Fournet M, Chabanne C, et al. Prognostic value of left atrial reservoir function in patients with severe aortic stenosis: a 2D speckle-tracking echocardiographic study. Eur Heart J Cardiovasc Imaging. 2015. doi:10.​1093/​ehjci/​jev230.
20.
Zurück zum Zitat Antoni ML, ten Brinke EA, Atary JZ, et al. Left atrial strain is related to adverse events in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Heart. 2011;97:1332–7.CrossRefPubMed Antoni ML, ten Brinke EA, Atary JZ, et al. Left atrial strain is related to adverse events in patients after acute myocardial infarction treated with primary percutaneous coronary intervention. Heart. 2011;97:1332–7.CrossRefPubMed
21.
Zurück zum Zitat Ersbøll M, Andersen MJ, Valeur N, et al. The prognostic value of left atrial peak reservoir strain in acute myocardial infarction is dependent on left ventricular longitudinal function and left atrial size. Circ Cardiovasc Imaging. 2013;6:26–33.CrossRefPubMed Ersbøll M, Andersen MJ, Valeur N, et al. The prognostic value of left atrial peak reservoir strain in acute myocardial infarction is dependent on left ventricular longitudinal function and left atrial size. Circ Cardiovasc Imaging. 2013;6:26–33.CrossRefPubMed
22.
Zurück zum Zitat Oki T, Miyoshi H, Oishi Y, et al. The impact of hypertension as a road to heart failure with preserved ejection fraction: diagnostic value of two-dimensional speckle tracking echocardiography for the early impairment of left atrial-left ventricular-arterial coupling. Curr Hypertens Rev. 2014;10:177–88.CrossRefPubMed Oki T, Miyoshi H, Oishi Y, et al. The impact of hypertension as a road to heart failure with preserved ejection fraction: diagnostic value of two-dimensional speckle tracking echocardiography for the early impairment of left atrial-left ventricular-arterial coupling. Curr Hypertens Rev. 2014;10:177–88.CrossRefPubMed
23.
Zurück zum Zitat Degirmenci H, Duman H, Demirelli S, et al. Assessment of effect of irbesartan and nebivolol on the left atrium volume and deformation in the patients with mild-moderate hypertension. Eur Rev Med Pharmacol Sci. 2014;18:781–9.PubMed Degirmenci H, Duman H, Demirelli S, et al. Assessment of effect of irbesartan and nebivolol on the left atrium volume and deformation in the patients with mild-moderate hypertension. Eur Rev Med Pharmacol Sci. 2014;18:781–9.PubMed
24.
Zurück zum Zitat Kurt M, Wang J, Torre-Amione G, et al. Left atrial function in diastolic heart failure. Circ Cardiovasc Imaging. 2009;2:10–5.CrossRefPubMed Kurt M, Wang J, Torre-Amione G, et al. Left atrial function in diastolic heart failure. Circ Cardiovasc Imaging. 2009;2:10–5.CrossRefPubMed
25.
Zurück zum Zitat Park CS, Kim YK, Song HC, et al. Effect of preload on left atrial function: evaluated by tissue Doppler and strain imaging. Eur Heart J Cardiovasc Imaging. 2012;13:938–47.CrossRefPubMed Park CS, Kim YK, Song HC, et al. Effect of preload on left atrial function: evaluated by tissue Doppler and strain imaging. Eur Heart J Cardiovasc Imaging. 2012;13:938–47.CrossRefPubMed
26.
Zurück zum Zitat Mukaide D, Tabata T, Kinoshita K, et al. Role of the left atrial function on the pseudonormalization of the transmitral flow velocity pattern evaluated by two-dimensional tissue tracking technique. J Cardiol. 2013;61:365–71.CrossRefPubMed Mukaide D, Tabata T, Kinoshita K, et al. Role of the left atrial function on the pseudonormalization of the transmitral flow velocity pattern evaluated by two-dimensional tissue tracking technique. J Cardiol. 2013;61:365–71.CrossRefPubMed
27.
Zurück zum Zitat Mochizuki A, Yuda S, Oi Y, et al. Assessment of left atrial deformation and synchrony by three-dimensional speckle-tracking echocardiography: comparative studies in healthy subjects and patients with atrial fibrillation. J Am Soc Echocardiogr. 2013;26:165–74.CrossRefPubMed Mochizuki A, Yuda S, Oi Y, et al. Assessment of left atrial deformation and synchrony by three-dimensional speckle-tracking echocardiography: comparative studies in healthy subjects and patients with atrial fibrillation. J Am Soc Echocardiogr. 2013;26:165–74.CrossRefPubMed
28.
Zurück zum Zitat Kobayashi Y, Okura H, Kobayashi Y, et al. Assessment of atrial synchrony in paroxysmal atrial fibrillation and impact of pulmonary vein isolation for atrial dyssynchrony and global strain by three-dimensional strain echocardiography. J Am Soc Echocardiogr. 2014;27:1193–9.CrossRefPubMed Kobayashi Y, Okura H, Kobayashi Y, et al. Assessment of atrial synchrony in paroxysmal atrial fibrillation and impact of pulmonary vein isolation for atrial dyssynchrony and global strain by three-dimensional strain echocardiography. J Am Soc Echocardiogr. 2014;27:1193–9.CrossRefPubMed
29.
Zurück zum Zitat Watanabe Y, Nakano Y, Hidaka T, et al. Mechanical and substrate abnormalities of the left atrium assessed by 3-dimensional speckle-tracking echocardiography and electroanatomic mapping system in patients with paroxysmal atrial fibrillation. Heart Rhythm. 2015;12:490–7.CrossRefPubMed Watanabe Y, Nakano Y, Hidaka T, et al. Mechanical and substrate abnormalities of the left atrium assessed by 3-dimensional speckle-tracking echocardiography and electroanatomic mapping system in patients with paroxysmal atrial fibrillation. Heart Rhythm. 2015;12:490–7.CrossRefPubMed
30.
Zurück zum Zitat Voigt JU, Pedrizzetti G, Lysyansky P, et al. Definitions for a common standard for 2D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. J Am Soc Echocardiogr. 2015;28:183–93.CrossRefPubMed Voigt JU, Pedrizzetti G, Lysyansky P, et al. Definitions for a common standard for 2D speckle tracking echocardiography: consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging. J Am Soc Echocardiogr. 2015;28:183–93.CrossRefPubMed
Metadaten
Titel
Clinical implications of left atrial function assessed by speckle tracking echocardiography
verfasst von
Satoshi Yuda
Atsuko Muranaka
Tetsuji Miura
Publikationsdatum
07.03.2016
Verlag
Springer Japan
Erschienen in
Journal of Echocardiography / Ausgabe 3/2016
Print ISSN: 1349-0222
Elektronische ISSN: 1880-344X
DOI
https://doi.org/10.1007/s12574-016-0283-7

Weitere Artikel der Ausgabe 3/2016

Journal of Echocardiography 3/2016 Zur Ausgabe

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.