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Translational Stroke Research
Erschienen in: Translational Stroke Research 4/2016

24.05.2016 | SI: Challenges and Controversies in Translational Stroke Research

Improving Reperfusion Therapies in the Era of Mechanical Thrombectomy

verfasst von: Italo Linfante, Marilyn J. Cipolla

Erschienen in: Translational Stroke Research | Ausgabe 4/2016

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Abstract

Recent positive clinical trials using mechanical thrombectomy proved that endovascular recanalization is an effective treatment for patients with acute stroke secondary to large vessel occlusions. The trials offer definite evidence that in acute ischemia recanalization is a powerful predictor of good outcome. However, even in the era of rapid and effective recanalization using endovascular approaches, the percentage of patients with good outcomes varies between 33 and 71 %. In addition, the number of patients who are eligible for endovascular thrombectomy is small and usually based on having salvageable tissue on imaging. There is therefore room for improvement to both enhance the effectiveness of current practice and expand treatment to a larger subset of stroke patients. In this review, we highlight some of the most promising approaches to improve endovascular therapy by combining with strategies to enhance collateral perfusion and vascular protection.
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Metadaten
Titel
Improving Reperfusion Therapies in the Era of Mechanical Thrombectomy
verfasst von
Italo Linfante
Marilyn J. Cipolla
Publikationsdatum
24.05.2016
Verlag
Springer US
Erschienen in
Translational Stroke Research / Ausgabe 4/2016
Print ISSN: 1868-4483
Elektronische ISSN: 1868-601X
DOI
https://doi.org/10.1007/s12975-016-0469-3

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