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Erschienen in: Translational Stroke Research 2/2017

23.05.2016 | Original Article

Association Between Dehydration and Short-Term Risk of Ischemic Stroke in Patients with Atrial Fibrillation

verfasst von: Joel N. Swerdel, Teresa M. Janevic, William J. Kostis, Ambarina Faiz, Nora M. Cosgrove, John B. Kostis, The Myocardial Infarction Data Acquisition System (MIDAS 27) Study Group

Erschienen in: Translational Stroke Research | Ausgabe 2/2017

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Abstract

Previous cross-sectional studies have demonstrated a higher incidence of dehydration in patients admitted for stroke suggesting a possible association. However, the temporality of the association has not been well established. We examined whether dehydration increases the risk of ischemic stroke in patients with a recent hospitalization for atrial fibrillation (AF). Data was from 1994 to 2012 from the Myocardial Infarction Data Acquisition System (MIDAS), a repository of in-patient records New Jersey hospitals, for AF hospitalizations (n = 1,282,787). Estimates for the association between AF hospitalization with/without dehydration and ischemic stroke within 30 days post-AF discharge were determined using log-linear multivariable modeling adjusting for socio-demographic factors and comorbid conditions. Within 10 days of discharge for AF, patients 18–80 years old (YO) with comorbid dehydration had a 60 % higher risk of ischemic stroke compared to AF patients without comorbid dehydration (adjusted risk ratio (ARR) 1.60, 95 % confidence interval (CI) 1.28–2.00). Eighteen- to 80-YO patients had a 34 % higher risk of ischemic stroke in days 11–20 post-AF discharge (ARR 1.34, 95 % CI 1.04, 1.74). There was no difference in the risk of stroke in 18–80-YO patients with or without prior dehydration during days 21–30 post-AF discharge. We also found no difference in the risk of ischemic stroke during any time period in patients over 80 YO. Dehydration may be a significant risk factor for ischemic stroke in patients 18–80 YO with AF.
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Metadaten
Titel
Association Between Dehydration and Short-Term Risk of Ischemic Stroke in Patients with Atrial Fibrillation
verfasst von
Joel N. Swerdel
Teresa M. Janevic
William J. Kostis
Ambarina Faiz
Nora M. Cosgrove
John B. Kostis
The Myocardial Infarction Data Acquisition System (MIDAS 27) Study Group
Publikationsdatum
23.05.2016
Verlag
Springer US
Erschienen in
Translational Stroke Research / Ausgabe 2/2017
Print ISSN: 1868-4483
Elektronische ISSN: 1868-601X
DOI
https://doi.org/10.1007/s12975-016-0471-9

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