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Erschienen in: The Journal of Obstetrics and Gynecology of India 3/2012

01.06.2012 | Original Article

Iron Deficiency Anemia in Pregnancy: Intravenous Versus Oral Route

verfasst von: Deeba Shafi, Shekhar V. Purandare, A. V. Sathe

Erschienen in: The Journal of Obstetrics and Gynecology of India | Ausgabe 3/2012

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Abstract

Objectives

The aim of this study was to compare the efficacy and safety of intravenous iron with oral iron in the treatment of iron deficiency anemia of pregnancy.

Methods

A randomized experimental study was conducted at K. J. Somaiya Hospital involving 200 pregnant women with iron deficiency anemia. In the intravenous group iron dose was calculated from: Total iron dose required (mg) = 2.4 × weight kg × target hemoglobin − actual hemoglobin) g/dl + 500.   Target hemoglobin was set at 12 g/dl. In the oral group patients received 200 mg oral ferrous ascorbate daily. Hemoglobin and serum ferritin were reviewed at 2, 4, and 6 weeks. Paired and independent t test was applied.

Results

The change in hemoglobin and ferritin levels from baseline was significantly higher in the intravenous group than the oral group at each measurement (P = 0.000).

Conclusion

Intravenous iron elevates hemoglobin and restores iron stores faster than oral iron, with no severe adverse reactions.
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Metadaten
Titel
Iron Deficiency Anemia in Pregnancy: Intravenous Versus Oral Route
verfasst von
Deeba Shafi
Shekhar V. Purandare
A. V. Sathe
Publikationsdatum
01.06.2012
Verlag
Springer-Verlag
Erschienen in
The Journal of Obstetrics and Gynecology of India / Ausgabe 3/2012
Print ISSN: 0971-9202
Elektronische ISSN: 0975-6434
DOI
https://doi.org/10.1007/s13224-012-0222-0

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