Introduction
Materials and methods
Patient population
Patient no. | Sex | Age | Type of malignancy | No. of positive PET findings | No. of lesions |
---|---|---|---|---|---|
1 | M | 36 | Malignant neoplasm of oral cavity | None | 0 |
2 | F | 67 | Non-Hodgkin’s lymphoma | None | 0 |
3 | M | 75 | Oesophageal cancer | Lung (1), pleura (1) | 2 |
4 | M | 58 | Malignant melanoma | Lymph node (6), adrenal gland (2), liver (1), bone (1), lung (1) | 11 |
5 | M | 76 | Pleural mesothelioma | Pleura (3) | 3 |
6 | F | 64 | Non-Hodgkin’s lymphoma | Lymph node (2) | 2 |
7 | M | 72 | Malignant melanoma | None | 0 |
8 | M | 75 | Lung cancer | Lymph node (2) | 2 |
9 | M | 53 | Oesophageal cancer | Lymph node (2) | 2 |
10 | F | 40 | Gynaecology tumour | Small bowl (1) | 1 |
11 | M | 42 | Stomach cancer | None | 0 |
12 | F | 74 | Breast cancer | Pleura (1), chest wall (1) | 2 |
13 | M | 52 | Malignant melanoma | None | 0 |
14 | M | 78 | Malignant melanoma | Lymph node (2) | 2 |
15 | F | 72 | Gynaecology tumour | Lymph node (1), vagina (1) | 3 |
16 | M | 55 | Malignant neoplasm of tongue | Tongue (1), lymph node (1), bone (1) | 3 |
17 | M | 80 | Malignant neoplasm of hypopharynx | Lymph node (2), lung (2) | 4 |
18 | M | 47 | Cancer of unknown origin | None | 0 |
19 | M | 59 | Malignant melanoma | None | 0 |
20 | M | 50 | Colorectal cancer | None | 0 |
21 | F | 86 | Cancer of unknown origin | Lymph node (5), sigmoid colon (1), tonsil (1) | 7 |
22 | F | 56 | Malignant neoplasm of thymus | Lymph node (2), thymus (1) | 3 |
23 | M | 67 | Pleural mesothelioma | Lymph node (1), bone (1), pleura (1) | 3 |
24 | M | 67 | Hodgkin’s lymphoma | Tonsil (1), sigmoid colon (1) | 2 |
25 | M | 66 | Malignant melanoma | Bone (1) | 1 |
26 | M | 34 | Lung cancer | Lung (2) | 2 |
27 | M | 50 | Hodgkin’s lymphoma | Lymph node (1), stomach (1) | 2 |
28 | M | 38 | Hodgkin’s lymphoma | Lymph node (2) | 2 |
29 | F | 57 | Cancer of unknown origin | Vagina (1) | 1 |
30 | M | 86 | Oesophageal cancer | None | 0 |
31 | F | 40 | Breast cancer | Breast (1) | 1 |
32 | M | 75 | Pleural mesothelioma | Lymph node (1), mesenterium (1), abdominal wall (1) | 3 |
33 | M | 19 | Hodgkin’s lymphoma | Colon (1) | 1 |
34 | M | 69 | Malignant melanoma | Cutaneous (1) | 1 |
35 | F | 53 | Colorectal cancer | Liver (2), lymph node (1), lung (1) | 4 |
36 | M | 44 | Lung cancer | Lymph node (2), lung (1) | 3 |
37 | M | 69 | Malignant melanoma | Lymph node (1) | 1 |
38 | F | 51 | Breast cancer | Lymph node (3), bone (2) | 5 |
39 | M | 70 | Stomach cancer | Bone (2), prostate (1), liver (1), stomach (1), lymph node (1) | 6 |
40 | F | 61 | Lung cancer | Lung (1), lymph node (1) | 2 |
41 | F | 60 | Lung cancer | None | 0 |
42 | W | 50 | Gynaecology tumour | Lymph node (2) | 2 |
43 | M | 61 | Malignant melanoma | None | 0 |
44 | F | 38 | Breast cancer | Lymph node (1) | 1 |
45 | M | 41 | Non-Hodgkin’s lymphoma | Lymph node (4) | 4 |
46 | M | 69 | Lung cancer | Lung (1) | 1 |
47 | M | 61 | Lung cancer | Lung (1), adrenal gland (1), bone (1) | 3 |
48 | M | 72 | Lung cancer | Lymph node (3), lung (1), liver (1) | 5 |
49 | F | 30 | Non-Hodgkin’s lymphoma | Lymph node (1) | 1 |
50 | M | 64 | Hodgkin’s lymphoma | Parotid gland (1) | 1 |
51 | F | 32 | Gynaecology tumour | None | 0 |
52 | F | 59 | Breast cancer | Lymph node (2), breast (1), thyroid gland (1) | 4 |
53 | M | 56 | Cancer of unknown origin | None | 0 |
54 | M | 71 | Malignant melanoma | Lymph node (2), mediastinum (2) | 4 |
55 | F | 46 | Breast cancer | Bone (2), breast (1) | 3 |
56 | M | 64 | Malignant neoplasm of larynx | None | 0 |
57 | M | 61 | Lung cancer | Lung (1) | 1 |
58 | M | 30 | Cancer of unknown origin | None | 0 |
59 | F | 49 | Breast cancer | None | 0 |
60 | F | 47 | Thyroid cancer | Lung (2) | 2 |
61 | F | 45 | Malignant neoplasm of peritoneum | Pleura (1), mesenterium (1) pelvic (1) | 3 |
62 | F | 59 | Malignant melanoma | None | 0 |
63 | M | 68 | Non-Hodgkin’s lymphoma | Lymph node (4) | 4 |
Imaging modalities
PET/CT
MR imaging
Image processing
Image analysis
Statistical analysis
Results
Overall lesion detection, conspicuity and lesion size
Conspicuity score | CT | MRI | ||
---|---|---|---|---|
Frequency | Percent | Frequency | Percent | |
1 | 17 | 13.5 | 27 | 21.4 |
2 | 29 | 23.0 | 23 | 18.3 |
3 | 26 | 20.6 | 30 | 23.8 |
4 | 54 | 42.9 | 46 | 36.5 |
Total | 126 | 100.0 | 126 | 100.0 |
Mean score | 2.93 | 2.75 |
Location (organ) based comparison of conspicuity and size
n
| CT | MRI | ||||
---|---|---|---|---|---|---|
Mean | Range | Mean | Range | |||
Axilla | 8 | Score | 3.88 | 3–4 | 3.88 | 3–4 |
Size [mm] | 9.36 | 5–13 | 9.46 | 4–14 | ||
Cervical | 17 | Score | 2.88 | 1–4 | 2.71 | 1–4 |
Size [mm] | 11.48 | 0–33 | 11.31 | 0–37 | ||
GIT + urogenital | 10 | Score | 2.00 | 1–4 | 2.40 | 1–4 |
Size [mm] | 28.22 | 0–55 | 25.03 | 0–48 | ||
Iliacal | 7 | Score | 4.00 | 4–4 | 3.86 | 3–4 |
Size [mm] | 13.53 | 4–22 | 13.87 | 4–22 | ||
Breast | 7 | Score | 2.57 | 1–4 | 1.86 | 1–3 |
Size [mm] | 7.80 | 0–16 | 8.97 | 0–16 | ||
Mediastinum | 19 | Score | 2.68 | 1–4 | 2.42 | 1–4 |
Size [mm] | 20.22 | 0–72 | 19.83 | 0–72 | ||
Mesenterium | 8 | Score | 2.88 | 2–4 | 2.38 | 1–4 |
Size [mm] | 23.24 | 5–80 | 20.88 | 0–82 | ||
Bone | 10 | Score | 2.80 | 1–4 | 2.10 | 1–4 |
Size [mm] | 15.17 | 7–13 | 9.94 | 0–36 | ||
Pleura | 7 | Score | 2.57 | 2–4 | 2.71 | 1–4 |
Size [mm] | 10.06 | 7–22 | 12.43 | 0–23 | ||
Lung | 15 | Score | 3.60 | 2–4 | 2.67 | 1–4 |
Size [mm] | 21.48 | 4–50 | 20.01 | 0–50 | ||
Retroperitoneum | 9 | Score | 3.67 | 2–4 | 3.78 | 3–4 |
Size [mm] | 27.96 | 7–80 | 27.14 | 7–76 |
Comparison of lesion conspicuity and size regarding lesion type
n
| CT | MRI | ||||
---|---|---|---|---|---|---|
Mean | Range | Mean | Range | |||
Tumour mass | 37 | Score | 3.08 | 1–4 | 2.78 | 1–4 |
Size [mm] | 22.81 | 0–55 | 22.13 | 0–50 | ||
Lymph node | 57 | Score | 3.26 | 1–4 | 3.01 | 1–4 |
Size [mm] | 14.32 | 0–80 | 13.81 | 0–82 | ||
Lesion | 17 | Score | 2.29 | 1–4 | 2.41 | 1–4 |
Size [mm] | 14.1 | 0–31 | 10.65 | 0–36 |