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A phantom study on the effects of target motion in non-gated kV-CBCT imaging

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Abstract

Kilo-voltage cone beam computed tomography (kV-CBCT) integrated with a linac can produce online volumetric and anatomical images for patient set-up and dosimetric analysis in adaptive radiotherapy. However CBCT is prone to motion artifacts. This study investigates the impact of target motion in CBCT imaging. To simulate respiratory movement, a dynamic phantom was moved in three-dimensions with a period of 4 s and two different amplitudes (PA1 and PA2). The targets of well defined geometries were made using wax. A reference image of the static target was achieved with fan beam CT. Using CBCT, the targets in static and dynamic modes were imaged under full-fan beam conditions. The length of average HU spread was reduced in range from 19.35 to 44.44% along the cranio-caudal direction of targets. The percentage volume loss of dynamic targets imaged using CBCT (for Hounsfield Units with window width −500 to 0) ranged from 14.35 to 30.95% for PA1 and 21.29 to 43.80% for PA2 in comparison with static targets imaged with fan beam CT. A significant loss of volumetric information may result for non-gated CBCT imaging of moving targets and may result in a systematic error in re-contouring when CBCT images are used for radiotherapy re-planning.

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References

  1. Xing L, Thorndyke B, Schreibmann E, Yang Y, Li TF, Kim GY et al (2006) Overview of image guided radiation therapy. Med Dosim 31:91–112

    Article  PubMed  Google Scholar 

  2. Jaffray DA, Siewerdsen JH (2000) Cone-beam computed tomography with a flat-panel imager: initial performance characterization. Med Phys 27:1311–1323

    Article  CAS  PubMed  Google Scholar 

  3. Jaffray DA, Siewerdsen JH, Wong JW, Martinez AA (2002) Flat panel cone-beam computed tomography for image-guided radiation therapy. Int J Radiat Oncol Biol Phys 53:1337–1349

    Article  PubMed  Google Scholar 

  4. Yan D, Lockman D, Brabbins D, Martinez A (2000) An off-line strategy for constructing a patient-specific planning target volume in adaptive treatment process for prostate cancer. Int J Radiat Oncol Biol Phys 48:289–302

    Article  CAS  PubMed  Google Scholar 

  5. Letourneau D, Wong R, Moseley D, Sharpe MB, Ansell S, Gospodarowicz M et al (2001) Online planning and delivery technique for radiotherapy of spine metastases using cone-beam CT: image quality and system performance. Int J Radiat Oncol Biol Phys 67:1229–1237

    Google Scholar 

  6. Yang Y, Schreibmann E, Li T, Wang C, Xing L (2007) Evaluation of on-board kV cone-beam CT (CBCT)-based dose calculation. Phys Med Biol 52:685–705

    Article  PubMed  Google Scholar 

  7. Chen GTY, Kung JH, Beaudette KP (2004) Artifacts in computed tomography scanning of moving objects. Semin Radiat Oncol 14:19–26

    Article  PubMed  Google Scholar 

  8. Keall PJ, Mageras GS, Balter JM, Emery RS, Forster KM, Jiang SB, Kapatoes JM, Kubo HD, Low DA, Murphy MJ, Murray BR, Ramsey CR, van Herk MB, Sastry Vedam S, Wong JW, Yorke E (2006) The management of respiratory motion in radiation oncology report of AAPM Task Group 76. Med Phys 33:3874–3900

    Article  PubMed  Google Scholar 

  9. Lu W, Parikh PJ, Hubenschmidt JP, Politte DG, Whiting BR, Bradley JD, Mutic S, Low DA (2005) Reduction of motion blurring artifacts using respiratory gated CT in sinogram space: a quantitative evaluation. Med Phys 32:3295–3304

    Article  PubMed  Google Scholar 

  10. Guckenberger M, Sweeney RA, Wilbert J, Krieger T, Richter A, Baier K et al (2008) Image-guided radiotherapy for liver cancer using respiratory-correlated computed tomography and cone-beam computed tomography. Int J Radiat Oncol Biol Phys 71:297–304

    PubMed  Google Scholar 

  11. Snoke JJ, Zijp L, Remeijer P, Van Herk M (2005) Repiratory correlated cone beam CT. Med Phys 32:1176–1186

    Article  Google Scholar 

  12. Siewerdsen JH, Jaffery DA (2001) Cone-beam computed tomography with a flat-panel imager: magnitude and effects of x-ray scatter. Med Phys 28:220–231

    Article  CAS  PubMed  Google Scholar 

  13. Yoo S, Ying FF (2006) Dosimetric feasibility of cone-beam CT-based treatment planning compared to CT-based treatment planning. Int J Radiat Oncol Biol Phys 66:1553–1561

    PubMed  Google Scholar 

  14. Tanyi JA, Fuss M, Varchena V, Lancaster JL, Salter BJ (2007) Phantom investigation of 3D motion-dependent volume aliasing during CT simulation for radiation therapy planning. Radiat Oncol 2:10

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Medical Physics Department, Cancer Institute (WIA), Chennai, India

    Sriram Padmanaban, Raghavendiran Boopathy, Bhuvana Kunjithapatham, Prabakar Sukumar & Vivekanandan Nagarajan

  2. B4 Sree Apartments, 4th link road, Sadasivam nagar, Madipakkam, Chennai, 600091, Tamil Nadu, India

    Sriram Padmanaban

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  1. Sriram Padmanaban
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  2. Raghavendiran Boopathy
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  3. Bhuvana Kunjithapatham
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  4. Prabakar Sukumar
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  5. Vivekanandan Nagarajan
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Correspondence to Sriram Padmanaban.

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Padmanaban, S., Boopathy, R., Kunjithapatham, B. et al. A phantom study on the effects of target motion in non-gated kV-CBCT imaging. Australas Phys Eng Sci Med 33, 59–64 (2010). https://doi.org/10.1007/s13246-010-0010-z

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  • DOI: https://doi.org/10.1007/s13246-010-0010-z

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