Skip to main content
Erschienen in: Updates in Surgery 2/2011

01.06.2011 | Case Report

Rare abdominal metastases from occult lobular breast cancer: report of two cases

verfasst von: Maria Sironi

Erschienen in: Updates in Surgery | Ausgabe 2/2011

Einloggen, um Zugang zu erhalten

Abstract

Intra-abdominal metastases from breast carcinomas are rarely reported in the literature. Least are those originating from occult breast primary. We report, one case of pancreatic metastasis and one case of metastatic infiltration of the colonic wall, both by occult lobular breast carcinoma. The first patient underwent pancreaticoduodenectomy for obstructive jaundice, with unexpected histological finding of infiltration of distal bile duct, pancreatic gland, portal vein and retroperitoneal soft tissue by lobular carcinoma of the breast. The second patient complained of diffuse abdominal pain associated with constipation and rectal bleeding and underwent endoscopic biopsy of three intestinal strictures, revealing metastatic lobular carcinoma with signet-ring cell morphology. In both cases, a subsequent complete diagnostic work-up demonstrated asymptomatic multiple breast nodules, diagnosed as lobular carcinoma by fine needle aspiration cytology.
Literatur
1.
Zurück zum Zitat Nazareno J, Taves D, Preiksaitis HG (2006) Metastatic breast cancer to the gastrointestinal tract: a case series and review of the literature. World J Gastroenterol 12(38):6219–6224PubMed Nazareno J, Taves D, Preiksaitis HG (2006) Metastatic breast cancer to the gastrointestinal tract: a case series and review of the literature. World J Gastroenterol 12(38):6219–6224PubMed
2.
Zurück zum Zitat Pectasides D, Psyrri A, Pliarchopoulou K, Floros T, Papaxoinis G, Skondra M, Papatsibas G, Macheras A, Athanasas G, Arapantoni-Datioti P, Economopoulos T (2009) Gastric metastases originating from breast cancer: report of 8 cases and review of the literature. Anticancer Res 29(11):4759–4763PubMed Pectasides D, Psyrri A, Pliarchopoulou K, Floros T, Papaxoinis G, Skondra M, Papatsibas G, Macheras A, Athanasas G, Arapantoni-Datioti P, Economopoulos T (2009) Gastric metastases originating from breast cancer: report of 8 cases and review of the literature. Anticancer Res 29(11):4759–4763PubMed
3.
Zurück zum Zitat Ghirarduzzi A, Sivelli R, Martella E, Bella M, De Simone B, Arcuri MF, Zannoni M, Del Rio P, Sianesi M (2010) Gastric metastasis from breast carcinoma. Report of three cases, diagnostic-therapeutic critical close examination and literature review. Ann Ital Chir 81(2):141–146PubMed Ghirarduzzi A, Sivelli R, Martella E, Bella M, De Simone B, Arcuri MF, Zannoni M, Del Rio P, Sianesi M (2010) Gastric metastasis from breast carcinoma. Report of three cases, diagnostic-therapeutic critical close examination and literature review. Ann Ital Chir 81(2):141–146PubMed
4.
Zurück zum Zitat Jones GE, Strauss DC, Forshaw MJ, Deere H, Mahedeva U, Mason RC (2007) Breast cancer metastasis to the stomach may mimic primary gastric cancer: report of two cases and review of the literature. Word J Surg Oncol 5:75–80CrossRef Jones GE, Strauss DC, Forshaw MJ, Deere H, Mahedeva U, Mason RC (2007) Breast cancer metastasis to the stomach may mimic primary gastric cancer: report of two cases and review of the literature. Word J Surg Oncol 5:75–80CrossRef
5.
Zurück zum Zitat Pérez Ochoa A, Sáez Hernáez F, Cajigas Fernández C, Pérez de la Lastra L, Ondiviela Gracia R, García de Polavieja M (2007) Pancreatic metastases from ductal and lobular carcinomas of the breast. Clin Transl Oncol 9(9):603–605PubMedCrossRef Pérez Ochoa A, Sáez Hernáez F, Cajigas Fernández C, Pérez de la Lastra L, Ondiviela Gracia R, García de Polavieja M (2007) Pancreatic metastases from ductal and lobular carcinomas of the breast. Clin Transl Oncol 9(9):603–605PubMedCrossRef
6.
Zurück zum Zitat Yousef GM, Gabril MY, Al-Haddad S, Mulligan AM, Honey RJ (2010) Invasive lobular carcinoma of the breast presenting as retroperitoneal fibrosis: a case report. J Med Case Reports 4:175–178PubMedCrossRef Yousef GM, Gabril MY, Al-Haddad S, Mulligan AM, Honey RJ (2010) Invasive lobular carcinoma of the breast presenting as retroperitoneal fibrosis: a case report. J Med Case Reports 4:175–178PubMedCrossRef
7.
Zurück zum Zitat Neal L, Sookhan N, Reynolds C (2009) Occult breast carcinoma presenting as gastrointestinal metastases. Case Report Med 2009:564756PubMed Neal L, Sookhan N, Reynolds C (2009) Occult breast carcinoma presenting as gastrointestinal metastases. Case Report Med 2009:564756PubMed
8.
Zurück zum Zitat Ciulla A, Castronovo G, Tomasello G, Maiorana AM, Russo L, Daniele E, Genova G (2008) Gastric metastases originating from occult breast lobular carcinoma: diagnostic and therapeutic problems. World J Surg Oncol 6:78–83PubMedCrossRef Ciulla A, Castronovo G, Tomasello G, Maiorana AM, Russo L, Daniele E, Genova G (2008) Gastric metastases originating from occult breast lobular carcinoma: diagnostic and therapeutic problems. World J Surg Oncol 6:78–83PubMedCrossRef
9.
Zurück zum Zitat Tang JY, Rampaul RS, Cheung KL (2008) The use of fulvestrant, a parenteral endocrine agent, in intestinal obstruction due to metastatic lobular breast carcinoma. World J Surg Oncol 6:128–131PubMedCrossRef Tang JY, Rampaul RS, Cheung KL (2008) The use of fulvestrant, a parenteral endocrine agent, in intestinal obstruction due to metastatic lobular breast carcinoma. World J Surg Oncol 6:128–131PubMedCrossRef
10.
Zurück zum Zitat Kobayashi T, Adachi S, Matsuda Y, Tominaga S (2007) A case of metastatic lobular breast carcinoma with detection of the primary tumor after ten years. Breast Cancer 14(3):333–336PubMedCrossRef Kobayashi T, Adachi S, Matsuda Y, Tominaga S (2007) A case of metastatic lobular breast carcinoma with detection of the primary tumor after ten years. Breast Cancer 14(3):333–336PubMedCrossRef
11.
Zurück zum Zitat Savanis G, Simatos G, Tzaida O, Tsikkinis C, Ammari S, Mylonas A, Kafasis E, Nisiotis A (2006) Gastrointestinal tract metastasis as first presentation of breast cancer. J BUON 11(1):79–81PubMed Savanis G, Simatos G, Tzaida O, Tsikkinis C, Ammari S, Mylonas A, Kafasis E, Nisiotis A (2006) Gastrointestinal tract metastasis as first presentation of breast cancer. J BUON 11(1):79–81PubMed
12.
Zurück zum Zitat Mylonas I, Janni W, Friese K, Gerber B (2004) Unexpected metastatic lobular carcinoma of the breast with intraabdominal spread and subsequent port site metastasis after diagnostic laparoscopy for exclusion of ovarian cancer. Gynecol Oncol 95:405–408PubMedCrossRef Mylonas I, Janni W, Friese K, Gerber B (2004) Unexpected metastatic lobular carcinoma of the breast with intraabdominal spread and subsequent port site metastasis after diagnostic laparoscopy for exclusion of ovarian cancer. Gynecol Oncol 95:405–408PubMedCrossRef
13.
Zurück zum Zitat Odzak A, Geliberti F, Farace G, Benitez S, Bistoletti R, Kozima S, Frider B (2001) Pancreatic tumor: an unusual presentation of an occult breast carcinoma. Acta Gastroenterol Latinoam 31(5):395–398PubMed Odzak A, Geliberti F, Farace G, Benitez S, Bistoletti R, Kozima S, Frider B (2001) Pancreatic tumor: an unusual presentation of an occult breast carcinoma. Acta Gastroenterol Latinoam 31(5):395–398PubMed
14.
Zurück zum Zitat Ferlicot S, Vincent-Salomon A, Medioni J, Genin P, Rosty C, Sigal-Zafrani B, Freneaux P, Jouve M, Thiery JP, Sastre-Garau X (2004) Wide metastatic spreading in infiltrating lobular carcinoma of the breast. Eur J Cancer 40:336–341PubMedCrossRef Ferlicot S, Vincent-Salomon A, Medioni J, Genin P, Rosty C, Sigal-Zafrani B, Freneaux P, Jouve M, Thiery JP, Sastre-Garau X (2004) Wide metastatic spreading in infiltrating lobular carcinoma of the breast. Eur J Cancer 40:336–341PubMedCrossRef
15.
Zurück zum Zitat Lee JH, Park S, Park HS, Park BW (2010) Clinicopathological features of infiltrating lobular carcinomas comparing with infiltrating ductal carcinomas: a case control study. World J Surg Oncol 8:34–40PubMedCrossRef Lee JH, Park S, Park HS, Park BW (2010) Clinicopathological features of infiltrating lobular carcinomas comparing with infiltrating ductal carcinomas: a case control study. World J Surg Oncol 8:34–40PubMedCrossRef
16.
Zurück zum Zitat Adsay NV, Andea A, Basturk O, Kilink N, Nassar H, Cheng JD (2004) Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature. Virchow Arch 444:527–535 Adsay NV, Andea A, Basturk O, Kilink N, Nassar H, Cheng JD (2004) Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature. Virchow Arch 444:527–535
17.
Zurück zum Zitat Asch MJ, Wiedel PD, Habif DV (1968) Gastrointestinal metastases from carcinoma of the breast. Autopsy study and 18 cases requiring operative intervention. Arch Surg 96(5):840–843PubMed Asch MJ, Wiedel PD, Habif DV (1968) Gastrointestinal metastases from carcinoma of the breast. Autopsy study and 18 cases requiring operative intervention. Arch Surg 96(5):840–843PubMed
18.
Zurück zum Zitat Crippa S, Angelini C, Mussi C, Bonardi C, Romano F, Sartori P, Uggeri F, Bovo G (2006) Surgical treatment of metastatic tumors to the pancreas: a single center experience and review of the literature. World J Surg 30(8):1536–1542PubMedCrossRef Crippa S, Angelini C, Mussi C, Bonardi C, Romano F, Sartori P, Uggeri F, Bovo G (2006) Surgical treatment of metastatic tumors to the pancreas: a single center experience and review of the literature. World J Surg 30(8):1536–1542PubMedCrossRef
19.
Zurück zum Zitat Sweeney AD, Fisher WE, Wu MF, Hilsenbeck SG, Brunicardi FC (2010) Value of pancreatic resection for cancer metastatic to the pancreas. J Surg Res 160(2):268–276PubMedCrossRef Sweeney AD, Fisher WE, Wu MF, Hilsenbeck SG, Brunicardi FC (2010) Value of pancreatic resection for cancer metastatic to the pancreas. J Surg Res 160(2):268–276PubMedCrossRef
20.
Zurück zum Zitat Güth U, Huang DJ, Dirnhofer S, Rochlitz C, Wight E (2009) Distant metastatic breast cancer as an incurable disease: a tenet with a need for revision. Cancer J 15(1):81–86PubMedCrossRef Güth U, Huang DJ, Dirnhofer S, Rochlitz C, Wight E (2009) Distant metastatic breast cancer as an incurable disease: a tenet with a need for revision. Cancer J 15(1):81–86PubMedCrossRef
Metadaten
Titel
Rare abdominal metastases from occult lobular breast cancer: report of two cases
verfasst von
Maria Sironi
Publikationsdatum
01.06.2011
Verlag
Springer Milan
Erschienen in
Updates in Surgery / Ausgabe 2/2011
Print ISSN: 2038-131X
Elektronische ISSN: 2038-3312
DOI
https://doi.org/10.1007/s13304-011-0047-x

Weitere Artikel der Ausgabe 2/2011

Updates in Surgery 2/2011 Zur Ausgabe

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.