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14.12.2017 | Case Report

HIV-associated opsoclonus-myoclonus-ataxia syndrome: early infection, immune reconstitution syndrome or secondary to other diseases? Case report and literature review

verfasst von: Bruno F. Guedes, Márcio A. A. Vieira Filho, Clarice Listik, Rafael B. Carra, Cristiane B. Pereira, Emanuelle R. da Silva, Hélio R. Gomes, José E. Vidal

Erschienen in: Journal of NeuroVirology | Ausgabe 1/2018

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Abstract

Opsoclonus-myoclonus-ataxia (OMA) syndrome is a debilitating autoimmune neurological disorder. Post-infectious opsoclonus-myoclonus-ataxia syndrome has been described with varying bacterial, spirochetal, and viral infections including several patients with HIV. However, specific immunopathological mechanisms that may lead to opsoclonus-myoclonus in HIV-positive patients are unknown.

We report a case of HIV-associated opsoclonus-myoclonus and early HIV infection. A review of published literature shows opsoclonus-myoclonus can occur during early infection, in immune reconstitution syndrome or in association with other infections, especially tuberculosis.

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Titel: HIV-associated opsoclonus-myoclonus-ataxia syndrome: early infection, immune reconstitution syndrome or secondary to other diseases? Case report and literature review
verfasst von: Bruno F. Guedes
Márcio A. A. Vieira Filho
Clarice Listik
Rafael B. Carra
Cristiane B. Pereira
Emanuelle R. da Silva
Hélio R. Gomes
José E. Vidal
Publikationsdatum: 14.12.2017
Verlag: Springer International Publishing
Erschienen in: Journal of NeuroVirology / Ausgabe 1/2018
Print ISSN: 1355-0284
Elektronische ISSN: 1538-2443
DOI: https://doi.org/10.1007/s13365-017-0603-3

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HIV-associated opsoclonus-myoclonus-ataxia syndrome: early infection, immune reconstitution syndrome or secondary to other diseases? Case report and literature review

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