nach oben

Infection

Erschienen in:

01.02.2014 | Case Report

Guillain–Barré syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c

verfasst von: N. Scharn, T. Ganzenmueller, J. J. Wenzel, R. Dengler, A. Heim, F. Wegner

Erschienen in: Infection | Ausgabe 1/2014

Einloggen, um Zugang zu erhalten

Abstract

In this report, we present a case of a 50-year-old immunocompetent man with Guillain–Barré syndrome (GBS) associated with an autochthonous hepatitis E virus (HEV) infection. The patient presented with tetraparesis and elevated liver enzymes. HEV infection was confirmed serologically and by polymerase chain reaction (PCR) from blood and stool. Phylogenetic analysis revealed a novel HEV genotype 3 isolate closely related to other subgenotype 3c isolates from pig livers purchased in Germany. This indicates an autochthonous, potentially food-related hepatitis E and is, to our knowledge, the first report about a neurological syndrome associated with an HEV subgenotype 3c infection.

McGrogan A, Madle GC, Seaman HE, de Vries CS. The epidemiology of Guillain–Barré syndrome worldwide. A systematic literature review. Neuroepidemiology. 2009;32:150–63.PubMedCrossRef

van Doorn PA, Ruts L, Jacobs BC. Clinical features, pathogenesis, and treatment of Guillain–Barré syndrome. Lancet Neurol. 2008;7:939–50.PubMedCrossRef

Pritchard J. What’s new in Guillain–Barré syndrome? Postgrad Med J. 2008;84:532–8.PubMedCrossRef

Cosi V, Versino M. Guillain–Barré syndrome. Neurol Sci. 2006;27:S47–51.PubMedCrossRef

Yuki N, Hartung HP. Guillain–Barré syndrome. N Engl J Med. 2012;366:2294–304.PubMedCrossRef

Cronin S, McNicholas R, Kavanagh E, Reid V, O’Rourke K. Anti-glycolipid GM2-positive Guillain–Barré syndrome due to hepatitis E infection. Ir J Med Sci. 2011;180:255–7.PubMedCrossRef

Kamar N, Bendall RP, Peron JM, Cintas P, Prudhomme L, Mansuy JM, et al. Hepatitis E virus and neurologic disorders. Emerg Infect Dis. 2011;17:173–9.PubMedCrossRef

Loly JP, Rikir E, Seivert M, Legros E, Defrance P, Belaiche J, et al. Guillain–Barré syndrome following hepatitis E. World J Gastroenterol. 2009;15:1645–7.PubMedCrossRef

Maurissen I, Jeurissen A, Strauven T, Sprengers D, De Schepper B. First case of anti-ganglioside GM1-positive Guillain–Barré syndrome due to hepatitis E virus infection. Infection. 2012;40:323–6.PubMedCrossRef

10.

Sood A, Midha V, Sood N. Guillain–Barré syndrome with acute hepatitis E. Am J Gastroenterol. 2000;95:3667–8.PubMed

11.

Tse AC, Cheung RT, Ho SL, Chan KH. Guillain–Barré syndrome associated with acute hepatitis E infection. J Clin Neurosci. 2012;19:607–8.PubMedCrossRef

12.

Purdy MA, Khudyakov YE. The molecular epidemiology of hepatitis E virus infection. Virus Res. 2011;161:31–9.PubMedCrossRef

13.

Dalton HR, Bendall R, Ijaz S, Banks M. Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis. 2008;8:698–709.PubMedCrossRef

14.

Aggarwal R, Naik S. Epidemiology of hepatitis E: current status. J Gastroenterol Hepatol. 2009;24:1484–93.PubMedCrossRef

15.

Wenzel JJ, Preiss J, Schemmerer M, Huber B, Plentz A, Jilg W. Detection of hepatitis E virus (HEV) from porcine livers in Southeastern Germany and high sequence homology to human HEV isolates. J Clin Virol. 2011;52:50–4.PubMedCrossRef

16.

Colson P, Borentain P, Motte A, Lagrange X, Kaba M, Henry M, et al. First human cases of hepatitis E infection with genotype 3c strains. J Clin Virol. 2007;40:318–20.PubMedCrossRef

17.

Rose N, Lunazzi A, Dorenlor V, Merbah T, Eono F, Eloit M, et al. High prevalence of Hepatitis E virus in French domestic pigs. Comp Immunol Microbiol Infect Dis. 2011;34:419–27.PubMedCrossRef

Titel: Guillain–Barré syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c
verfasst von: N. Scharn
T. Ganzenmueller
J. J. Wenzel
R. Dengler
A. Heim
F. Wegner
Publikationsdatum: 01.02.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: Infection / Ausgabe 1/2014
Print ISSN: 0300-8126
Elektronische ISSN: 1439-0973
DOI: https://doi.org/10.1007/s15010-013-0448-5

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

^{Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag}

Kostenlos registrieren

Neu im Fachgebiet Innere Medizin

19.04.2024 | Vorhofflimmern | Nachrichten

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

Newsletter bestellen

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Guillain–Barré syndrome associated with autochthonous infection by hepatitis E virus subgenotype 3c

Abstract

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Parodontalbehandlung verbessert Prognose bei Katheterablation

Prostatakarzinom: EU initiiert neues Screeningkonzept

Blasenkarzinom – Biomarker statt Zytologie?

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Update Innere Medizin

Live-Webinar: Aktuelle Leitlinien bei Herz-Kreislauf-Erkrankungen

Springer Medizin

Abstract

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Weitere Artikel der Ausgabe 1/2014

Effective strategy for managing H7N9 virus infection

Isolated mediastinal necrotizing granulomatous lymphadenopathy due to cat-scratch disease

Genotypic testing on HIV-1 DNA as a tool to assess HIV-1 co-receptor usage in clinical practice: results from the DIVA study group

Effective strategy for managing H7N9 virus infection

New Italian guidelines for malaria prophylaxis in travellers to endemic areas

Trauma is associated with a better prognosis in intensive care patients with Acinetobacter infections

Leitlinien kompakt für die Innere Medizin

Neu im Fachgebiet Innere Medizin

Parodontalbehandlung verbessert Prognose bei Katheterablation

Prostatakarzinom: EU initiiert neues Screeningkonzept

Blasenkarzinom – Biomarker statt Zytologie?

Antihypertensiva schützen auch alte Menschen noch vor Demenz

Update Innere Medizin