Introduction
Methods
1 | Please list the full name of your institution (for de-duplicating purposes) |
2 | How many inpatient beds does your institution currently have? |
3 | Which of the following best describes the location of your institution? |
Urban, Suburban, Rural | |
4 | Was the patient’s age under 90 years old? If yes, please list the patient’s age |
5 | Sex: male or female |
6 | Which antimicrobial was unavailable for your patient? |
7 | Please list the infection for which treatment or prophylaxis was needed |
8 | What adverse event did your patient experience? |
9 | Please attribute the causality of the shortage to the adverse event that occurred in your patient |
Unrelated: the adverse event is clearly not related to the shortage | |
Unlikely: the adverse event is doubtfully related to the shortage | |
Possible: the adverse event may be related to the shortage | |
Probable: the adverse event is likely related to the shortage | |
10 | Please attribute a severity to the adverse event that occurred in your patient |
Death | |
Disabling | |
Hospitalization | |
Life threatening | |
Required intervention | |
Other (please specify) | |
11 | What was the final patient outcome? Please check all that apply |
Death | |
Treatment failure/development of resistance | |
Readmission due to treatment failure | |
Increased length of hospitalization | |
Patient transferred to an institution with a supply of antimicrobial | |
Delay of therapy | |
Suboptimal treatment | |
Other (please specify) |
Results
Patient | Age (sex) | Antimicrobial on shortage | Infection being treated | ADE experienced | Causality due to shortage | Severity of ADE | Final patient outcome |
---|---|---|---|---|---|---|---|
1 | <90 (F) | Sulfamethoxazole–trimethoprim IV |
Stenotrophomonas maltophilia bacteremia | Death | Unlikely | Death | Death |
2 | 45 (F) | Sulfamethoxazole-trimethoprim IV | PCP pneumonia | Nausea/vomiting/diarrhea when given high oral dose | Possible | Required intervention | Delay of therapy |
3 | <90 (F) | Gentamicin | Empiric neonatal sepsis | 1 h delay of treatment | Probable | Required intervention | Readmission |
4 | 25 (M) | Foscarnet | CMV colitis | Untreatable due to resistance | Probable | Other: disease still present | Other: obtained foscarnet outside the United States |