Erschienen in:
10.07.2020 | Review Article
Alternative Clinical Indications of Botulinum Toxin
verfasst von:
Tina S. Alster, Iris S. Harrison
Erschienen in:
American Journal of Clinical Dermatology
|
Ausgabe 6/2020
Einloggen, um Zugang zu erhalten
Abstract
Botulinum toxin type A (BoNTA) is a powerful neurotoxin that inhibits acetylcholine release from presynaptic vesicles. The potency and safety profile of BoNTA grant the toxin vast therapeutic potential. It has been used off-label for a variety of dermatologic conditions. This review aims to analyze published literature regarding the benefits and risks of the off-label use of BoNTA beyond facial lines, including eccrine hidrocystomas, enlarged pores, keloids and hypertrophic scars, hidradenitis suppurativa, hyperhidrosis, masseter muscle hypertrophy, and salivary gland hypertrophy, among others. A MEDLINE search from January 2000 to December 2019 was conducted on the off-label uses of botulinum toxin in dermatology.