Skip to main content
Erschienen in: Sports Medicine 9/2014

01.09.2014 | Systematic Review

Predictors of Primary Achilles Tendon Ruptures

verfasst von: Femke M. A. P. Claessen, Robert-Jan de Vos, Max Reijman, Duncan E. Meuffels

Erschienen in: Sports Medicine | Ausgabe 9/2014

Einloggen, um Zugang zu erhalten

Abstract

Background

The Achilles tendon is the strongest tendon in the human body. The incidence of Achilles tendon ruptures appears to be increasing.

Objectives

The aim of this review was to systematically summarize predictors influencing Achilles tendon rupture (ATR) risk.

Methods

A systematic literature search was performed of reported determinants influencing the ATR risk. Studies were eligible if there was: (i) description of determinants predicting ATR; (ii) an outcome defined as ATR; (iii) any study design with at least ten adults included with ATR; (iv) use of statistical tests regarding differences between patients with an ATR and healthy controls; (v) a full text article available; (vi) an article written in English, German or Dutch. Quality assessment was done using a standardized criteria set. Best-evidence synthesis was performed.

Results

We included 31 studies, of which two (6.5 %) were considered high-quality studies. Moderate evidence was found for increased ATR risk and decreased fibril size of Achilles tendon.

Conclusion

Based on the results of this systematic review there is moderate evidence that decreased tendon fibril size increases the ATR risk. There is limited evidence for many other factors, some of which are modifiable, such as increased body weight, oral corticosteroid use and quinolone use and living in an urban area, and therefore may be of interest in future studies. Furthermore, these results showed that more high-quality studies are needed for evaluating the determinants influencing the ATR risk.
Literatur
1.
Zurück zum Zitat Jarvinen TAH, Kannus P, Maffulli N, Khan KM. Achilles tendon disorders: etiology and epidemiology. Foot Ankle Clin. 2005;10(2):255–66.PubMedCrossRef Jarvinen TAH, Kannus P, Maffulli N, Khan KM. Achilles tendon disorders: etiology and epidemiology. Foot Ankle Clin. 2005;10(2):255–66.PubMedCrossRef
2.
Zurück zum Zitat Leppilahti J, Puranen J, Orava S. Incidence of Achilles tendon rupture. Acta Orthop Scand. 1996;67(3):277–9.PubMedCrossRef Leppilahti J, Puranen J, Orava S. Incidence of Achilles tendon rupture. Acta Orthop Scand. 1996;67(3):277–9.PubMedCrossRef
3.
Zurück zum Zitat Maffulli N, Waterston SW, Squair J, Reaper J, Douglas AS. Changing incidence of Achilles tendon rupture in Scotland: a 15-year study. Clin J Sport Med. 1999;9(3):157–60.PubMedCrossRef Maffulli N, Waterston SW, Squair J, Reaper J, Douglas AS. Changing incidence of Achilles tendon rupture in Scotland: a 15-year study. Clin J Sport Med. 1999;9(3):157–60.PubMedCrossRef
4.
Zurück zum Zitat Houshian S, Tscherning T, Riegels-Nielsen P. The epidemiology of Achilles tendon rupture in a Danish county. Injury. 1998;29(9):651–4.PubMedCrossRef Houshian S, Tscherning T, Riegels-Nielsen P. The epidemiology of Achilles tendon rupture in a Danish county. Injury. 1998;29(9):651–4.PubMedCrossRef
5.
6.
Zurück zum Zitat Suchak AA, Bostick G, Reid D, Blitz S, Jomha N. The incidence of Achilles tendon ruptures in Edmonton, Canada. Foot Ankle Int. 2005;26(11):932–6.PubMed Suchak AA, Bostick G, Reid D, Blitz S, Jomha N. The incidence of Achilles tendon ruptures in Edmonton, Canada. Foot Ankle Int. 2005;26(11):932–6.PubMed
7.
Zurück zum Zitat Nyyssonen T, Luthje P, Kroger H. The increasing incidence and difference in sex distribution of Achilles tendon rupture in Finland in 1987–1999. Scand J Surg. 2008;97(3):272–5.PubMed Nyyssonen T, Luthje P, Kroger H. The increasing incidence and difference in sex distribution of Achilles tendon rupture in Finland in 1987–1999. Scand J Surg. 2008;97(3):272–5.PubMed
8.
Zurück zum Zitat Kannus P, Natri A. Etiology and pathophysiology of tendon ruptures in sports. Scand J Med Sci Sports. 1997;7(2):107–12.PubMedCrossRef Kannus P, Natri A. Etiology and pathophysiology of tendon ruptures in sports. Scand J Med Sci Sports. 1997;7(2):107–12.PubMedCrossRef
9.
Zurück zum Zitat Anders Nillius S, Nilsson BE, Westlin NE. The incidence of Achilles tendon rupture. Acta Orthop Scand. 47(1):118–21. Anders Nillius S, Nilsson BE, Westlin NE. The incidence of Achilles tendon rupture. Acta Orthop Scand. 47(1):118–21.
10.
Zurück zum Zitat Davis JJ, Mason KT, Clark DA. Achilles tendon ruptures stratified by age, race, and cause of injury among active duty U.S. military members. Mil Med. 1999;164(12):872–3.PubMed Davis JJ, Mason KT, Clark DA. Achilles tendon ruptures stratified by age, race, and cause of injury among active duty U.S. military members. Mil Med. 1999;164(12):872–3.PubMed
11.
Zurück zum Zitat Parekh SG, Wray WH 3rd, Brimmo O, Sennett BJ, Wapner KL. Epidemiology and outcomes of Achilles tendon ruptures in the National Football League. Foot Ankle Spec. 2009;2(6):283–6.PubMedCrossRef Parekh SG, Wray WH 3rd, Brimmo O, Sennett BJ, Wapner KL. Epidemiology and outcomes of Achilles tendon ruptures in the National Football League. Foot Ankle Spec. 2009;2(6):283–6.PubMedCrossRef
12.
Zurück zum Zitat Flik KR, Bush-Joseph CA, Bach BR Jr. Complete rupture of large tendons: risk factors, signs, and definitive treatment. Phys Sportsmed. 2005;33(8):19–28 + 47. Flik KR, Bush-Joseph CA, Bach BR Jr. Complete rupture of large tendons: risk factors, signs, and definitive treatment. Phys Sportsmed. 2005;33(8):19–28 + 47.
13.
Zurück zum Zitat Kannus P, Jozsa L. Histopathological changes preceding spontaneous rupture of a tendon. A controlled study of 891 patients. J Bone Joint Surg Am. 1991;73(10):1507–25.PubMed Kannus P, Jozsa L. Histopathological changes preceding spontaneous rupture of a tendon. A controlled study of 891 patients. J Bone Joint Surg Am. 1991;73(10):1507–25.PubMed
14.
Zurück zum Zitat Komi PV, Fukashiro S, Jarvinen M. Biomechanical loading of Achilles tendon during normal locomotion. Clin Sports Med. 1992;11(3):521–31.PubMed Komi PV, Fukashiro S, Jarvinen M. Biomechanical loading of Achilles tendon during normal locomotion. Clin Sports Med. 1992;11(3):521–31.PubMed
15.
Zurück zum Zitat Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health. 1998;52(6):377–84.PubMedCrossRefPubMedCentral Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health. 1998;52(6):377–84.PubMedCrossRefPubMedCentral
16.
Zurück zum Zitat Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J. Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg. 2003;73(9):712–6.PubMedCrossRef Slim K, Nini E, Forestier D, Kwiatkowski F, Panis Y, Chipponi J. Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg. 2003;73(9):712–6.PubMedCrossRef
17.
Zurück zum Zitat Deeks JJ, Dinnes J, D’Amico R, Sowden AJ, Sakarovitch C, Song F, et al. Evaluating non-randomised intervention studies. Health Technol Assess. 2003;7(27):iii-x, 1–173. Deeks JJ, Dinnes J, D’Amico R, Sowden AJ, Sakarovitch C, Song F, et al. Evaluating non-randomised intervention studies. Health Technol Assess. 2003;7(27):iii-x, 1–173.
18.
Zurück zum Zitat van Tulder M, Furlan A, Bombardier C, Bouter L. Updated method guidelines for systematic reviews in the cochrane collaboration back review group. Spine (Phila Pa 1976). 2003;28(12):1290–9. van Tulder M, Furlan A, Bombardier C, Bouter L. Updated method guidelines for systematic reviews in the cochrane collaboration back review group. Spine (Phila Pa 1976). 2003;28(12):1290–9.
19.
Zurück zum Zitat Magnusson SP, Qvortrup K, Larsen JO, Rosager S, Hanson P, Aagaard P, et al. Collagen fibril size and crimp morphology in ruptured and intact Achilles tendons. Matrix Biol. 2002;21(4):369–77.PubMedCrossRef Magnusson SP, Qvortrup K, Larsen JO, Rosager S, Hanson P, Aagaard P, et al. Collagen fibril size and crimp morphology in ruptured and intact Achilles tendons. Matrix Biol. 2002;21(4):369–77.PubMedCrossRef
20.
Zurück zum Zitat Raleigh SM, Van Der Merwe L, Ribbans WJ, Smith RKW, Schwellnus MP, Collins M. Variants within the MMP3 gene are associated with Achilles tendinopathy: possible interaction with the COL5A1 gene. Br J Sports Med. 2009;43(7):514–20.PubMedCrossRef Raleigh SM, Van Der Merwe L, Ribbans WJ, Smith RKW, Schwellnus MP, Collins M. Variants within the MMP3 gene are associated with Achilles tendinopathy: possible interaction with the COL5A1 gene. Br J Sports Med. 2009;43(7):514–20.PubMedCrossRef
21.
Zurück zum Zitat Corrao G, Zambon A, Bertu L, Mauri A, Paleari V, Rossi C, et al. Evidence of tendinitis provoked by fluoroquinolone treatment a case-control study. Drug Saf. 2006;29(10):889–96.PubMedCrossRef Corrao G, Zambon A, Bertu L, Mauri A, Paleari V, Rossi C, et al. Evidence of tendinitis provoked by fluoroquinolone treatment a case-control study. Drug Saf. 2006;29(10):889–96.PubMedCrossRef
22.
Zurück zum Zitat Van der Linden PD, Sturkenboom MCJM, Herings RMC, Leufkens HMG, Rowlands S, Stricker BHC. Increased risk of Achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids. Arch Intern Med. 2003;163(15):1801–7.PubMedCrossRef Van der Linden PD, Sturkenboom MCJM, Herings RMC, Leufkens HMG, Rowlands S, Stricker BHC. Increased risk of Achilles tendon rupture with quinolone antibacterial use, especially in elderly patients taking oral corticosteroids. Arch Intern Med. 2003;163(15):1801–7.PubMedCrossRef
23.
Zurück zum Zitat Wise BL, Peloquin C, Choi H, Lane NE, Zhang Y. Impact of age, sex, obesity, and steroid use on quinolone-associated tendon disorders. Am J Med. 2012;125(12):1228.e3-.e. Wise BL, Peloquin C, Choi H, Lane NE, Zhang Y. Impact of age, sex, obesity, and steroid use on quinolone-associated tendon disorders. Am J Med. 2012;125(12):1228.e3-.e.
24.
Zurück zum Zitat Kettunen JA, Kujala UM, Kaprio J, Sarna S. Health of master track and field athletes: a 16-year follow-up study. Clin J Sport Med. 2006;16(2):142–8.PubMedCrossRef Kettunen JA, Kujala UM, Kaprio J, Sarna S. Health of master track and field athletes: a 16-year follow-up study. Clin J Sport Med. 2006;16(2):142–8.PubMedCrossRef
25.
Zurück zum Zitat Posthumus M, September AV, Schwellnus MP, Collins M. Investigation of the Sp1-binding site polymorphism within the COL1A1 gene in participants with Achilles tendon injuries and controls. J Sci Med Sports. 2009;12(1):184–9.CrossRef Posthumus M, September AV, Schwellnus MP, Collins M. Investigation of the Sp1-binding site polymorphism within the COL1A1 gene in participants with Achilles tendon injuries and controls. J Sci Med Sports. 2009;12(1):184–9.CrossRef
26.
Zurück zum Zitat Jozsa L, Kvist M, Balint BJ, Reffy A, Jarvinen M, Lehto M, et al. The role of recreational sport activity in Achilles tendon rupture. A clinical, pathoanatomical, and sociological study of 292 cases. Am J Sports Med. 1989;17(3):338–43. Jozsa L, Kvist M, Balint BJ, Reffy A, Jarvinen M, Lehto M, et al. The role of recreational sport activity in Achilles tendon rupture. A clinical, pathoanatomical, and sociological study of 292 cases. Am J Sports Med. 1989;17(3):338–43.
27.
Zurück zum Zitat Owens B, Mountcastle S, White D. Racial differences in tendon rupture incidence. Int J Sports Med. 2007;28(7):617–20.PubMedCrossRef Owens B, Mountcastle S, White D. Racial differences in tendon rupture incidence. Int J Sports Med. 2007;28(7):617–20.PubMedCrossRef
28.
Zurück zum Zitat Seeger JD, West WA, Fife D, Noel GJ, Johnson LN, Walker AM. Achilles tendon rupture and its association with fluoroquinolone antibiotics and other potential risk factors in a managed care population. Pharmacoepidemiol Drug Saf. 2006;15(11):784–92.PubMedCrossRef Seeger JD, West WA, Fife D, Noel GJ, Johnson LN, Walker AM. Achilles tendon rupture and its association with fluoroquinolone antibiotics and other potential risk factors in a managed care population. Pharmacoepidemiol Drug Saf. 2006;15(11):784–92.PubMedCrossRef
29.
Zurück zum Zitat Vosseller JT, Ellis SJ, Levine DS, Kennedy JG, Elliott AJ, Deland JT, et al. Achilles tendon rupture in women. Foot Ankle Int. 2013;34(1):49–53.PubMed Vosseller JT, Ellis SJ, Levine DS, Kennedy JG, Elliott AJ, Deland JT, et al. Achilles tendon rupture in women. Foot Ankle Int. 2013;34(1):49–53.PubMed
30.
Zurück zum Zitat Raikin SM, Garras DN, Krapchev PV. Achilles tendon injuries in a United States population. Foot Ankle Int. 2013;34(4):475–80.PubMedCrossRef Raikin SM, Garras DN, Krapchev PV. Achilles tendon injuries in a United States population. Foot Ankle Int. 2013;34(4):475–80.PubMedCrossRef
31.
Zurück zum Zitat Kraemer R, Wuerfel W, Lorenzen J, Busche M, Vogt PM, Knobloch K. Analysis of hereditary and medical risk factors in Achilles tendinopathy and Achilles tendon ruptures: a matched pair analysis. Arch Orthop Trauma Surg. 2012;132(6):847–53.PubMedCrossRef Kraemer R, Wuerfel W, Lorenzen J, Busche M, Vogt PM, Knobloch K. Analysis of hereditary and medical risk factors in Achilles tendinopathy and Achilles tendon ruptures: a matched pair analysis. Arch Orthop Trauma Surg. 2012;132(6):847–53.PubMedCrossRef
32.
Zurück zum Zitat Maffulli N, Irwin AS, Kenward MG, Smith F, Porter RW. Achilles tendon rupture and sciatica: a possible correlation. Br J Sports Med. 1998;32(2):174–7.PubMedCrossRefPubMedCentral Maffulli N, Irwin AS, Kenward MG, Smith F, Porter RW. Achilles tendon rupture and sciatica: a possible correlation. Br J Sports Med. 1998;32(2):174–7.PubMedCrossRefPubMedCentral
33.
Zurück zum Zitat Tallon C, Maffulli N, Ewen SWB. Ruptured Achilles tendons are significantly more degenerated than tendinopathic tendons. Med Sci Sports Exerc. 2001;33(12):1983–90.PubMedCrossRef Tallon C, Maffulli N, Ewen SWB. Ruptured Achilles tendons are significantly more degenerated than tendinopathic tendons. Med Sci Sports Exerc. 2001;33(12):1983–90.PubMedCrossRef
34.
Zurück zum Zitat Hansen P, Kovanen V, Holmich P, Krogsgaard M, Hansson P, Dahl M, et al. Micromechanical properties and collagen composition of ruptured human Achilles tendon. Am J Sports Med. 2013;41(2):437–43.PubMedCrossRef Hansen P, Kovanen V, Holmich P, Krogsgaard M, Hansson P, Dahl M, et al. Micromechanical properties and collagen composition of ruptured human Achilles tendon. Am J Sports Med. 2013;41(2):437–43.PubMedCrossRef
35.
Zurück zum Zitat Maffulli N, Ewen SW, Waterston SW, Reaper J, Barrass V. Tenocytes from ruptured and tendinopathic Achilles tendons produce greater quantities of type III collagen than tenocytes from normal Achilles tendons. An in vitro model of human tendon healing. Am J Sports Med. 2000;28(4):499–505. Maffulli N, Ewen SW, Waterston SW, Reaper J, Barrass V. Tenocytes from ruptured and tendinopathic Achilles tendons produce greater quantities of type III collagen than tenocytes from normal Achilles tendons. An in vitro model of human tendon healing. Am J Sports Med. 2000;28(4):499–505.
36.
Zurück zum Zitat Jarvinen TAH, Jarvinen TLN, Kannus P, Jozsa L, Jarvinen M. Collagen fibres of the spontaneously ruptured human tendons display decreased thickness and crimp angle. J Orthop Res. 2004;22(6):1303–9.PubMedCrossRef Jarvinen TAH, Jarvinen TLN, Kannus P, Jozsa L, Jarvinen M. Collagen fibres of the spontaneously ruptured human tendons display decreased thickness and crimp angle. J Orthop Res. 2004;22(6):1303–9.PubMedCrossRef
37.
Zurück zum Zitat Bleakney RR, Tallon C, Wong JK, Lim KP, Maffulli N. Long-term ultrasonographic features of the Achilles tendon after rupture. Clin J Sport Med. 2002;12(5):273–8.PubMedCrossRef Bleakney RR, Tallon C, Wong JK, Lim KP, Maffulli N. Long-term ultrasonographic features of the Achilles tendon after rupture. Clin J Sport Med. 2002;12(5):273–8.PubMedCrossRef
38.
Zurück zum Zitat Maffulli N, Barrass V, Ewen SW. Light microscopic histology of achilles tendon ruptures. A comparison with unruptured tendons. Am J Sports Med. 2000;28(6):857–63. Maffulli N, Barrass V, Ewen SW. Light microscopic histology of achilles tendon ruptures. A comparison with unruptured tendons. Am J Sports Med. 2000;28(6):857–63.
39.
Zurück zum Zitat Leppilahti J, Korpelainen R, Karpakka J, Kvist M, Orava S. Ruptures of the Achilles tendon: relationship to inequality in length of legs and to patterns in the foot and ankle. Foot Ankle Int. 1998;19(10):683–7.PubMedCrossRef Leppilahti J, Korpelainen R, Karpakka J, Kvist M, Orava S. Ruptures of the Achilles tendon: relationship to inequality in length of legs and to patterns in the foot and ankle. Foot Ankle Int. 1998;19(10):683–7.PubMedCrossRef
40.
Zurück zum Zitat Jones GC, Corps AN, Pennington CJ, Clark IM, Edwards DR, Bradley MM, et al. Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon. Arthritis Rheum. 2006;54(3):832–42.PubMedCrossRef Jones GC, Corps AN, Pennington CJ, Clark IM, Edwards DR, Bradley MM, et al. Expression profiling of metalloproteinases and tissue inhibitors of metalloproteinases in normal and degenerate human achilles tendon. Arthritis Rheum. 2006;54(3):832–42.PubMedCrossRef
41.
Zurück zum Zitat Petersen W, Pufe T, Zantop T, Tillmann B, Tsokos M, Mentlein R. Expression of VEGFR-1 and VEGFR-2 in degenerative Achilles tendons. Clin Orthop Relat Res. 2004;420:286–91.PubMedCrossRef Petersen W, Pufe T, Zantop T, Tillmann B, Tsokos M, Mentlein R. Expression of VEGFR-1 and VEGFR-2 in degenerative Achilles tendons. Clin Orthop Relat Res. 2004;420:286–91.PubMedCrossRef
42.
Zurück zum Zitat Legerlotz K, Jones ER, Screen HR, Riley GP. Increased expression of IL-6 family members in tendon pathology. Rheumatology (Oxford). 2012;51(7):1161–5.PubMedCrossRefPubMedCentral Legerlotz K, Jones ER, Screen HR, Riley GP. Increased expression of IL-6 family members in tendon pathology. Rheumatology (Oxford). 2012;51(7):1161–5.PubMedCrossRefPubMedCentral
43.
Zurück zum Zitat Kujala UM, Jarvinen M, Natri A, Lehto M, Nelimarkka O, Hurme M, et al. ABO blood and musculoskeletal injuries. Injury. 1992;23(2):131–3.PubMedCrossRef Kujala UM, Jarvinen M, Natri A, Lehto M, Nelimarkka O, Hurme M, et al. ABO blood and musculoskeletal injuries. Injury. 1992;23(2):131–3.PubMedCrossRef
44.
Zurück zum Zitat Maffulli N, Reaper JA, Waterston SW, Ahya T. ABO blood groups and achilles tendon rupture in the Grampian Region of Scotland. Clin J Sport Med. 2000;10(4):269–71.PubMedCrossRef Maffulli N, Reaper JA, Waterston SW, Ahya T. ABO blood groups and achilles tendon rupture in the Grampian Region of Scotland. Clin J Sport Med. 2000;10(4):269–71.PubMedCrossRef
45.
Zurück zum Zitat Raunest J, Burrig KF, Derra E. Pathogenesis of Achilles tendon rupture. Chirurg. 1990;61(11):815–9.PubMed Raunest J, Burrig KF, Derra E. Pathogenesis of Achilles tendon rupture. Chirurg. 1990;61(11):815–9.PubMed
46.
Zurück zum Zitat Kujala UM, Sarna S, Kaprio J. Cumulative incidence of achilles tendon rupture and tendinopathy in male former elite athletes. Clin J Sport Med. 2005;15(3):133–5.PubMedCrossRef Kujala UM, Sarna S, Kaprio J. Cumulative incidence of achilles tendon rupture and tendinopathy in male former elite athletes. Clin J Sport Med. 2005;15(3):133–5.PubMedCrossRef
47.
Zurück zum Zitat Sode J, Obel N, Hallas J, Lassen A. Use of fluroquinolone and risk of Achilles tendon rupture: a population-based cohort study. Eur J Clin Pharmacol. 2007;63(5):499–503.PubMedCrossRef Sode J, Obel N, Hallas J, Lassen A. Use of fluroquinolone and risk of Achilles tendon rupture: a population-based cohort study. Eur J Clin Pharmacol. 2007;63(5):499–503.PubMedCrossRef
48.
Zurück zum Zitat Parry DA, Craig AS. Collagen fibrils and elastic fibers in rat-tail tendon: an electron microscopic investigation. Biopolymers. 1978;17(4):843–5.PubMedCrossRef Parry DA, Craig AS. Collagen fibrils and elastic fibers in rat-tail tendon: an electron microscopic investigation. Biopolymers. 1978;17(4):843–5.PubMedCrossRef
49.
Zurück zum Zitat Parry DA, Barnes GR, Craig AS. A comparison of the size distribution of collagen fibrils in connective tissues as a function of age and a possible relation between fibril size distribution and mechanical properties. Proc R Soc Lond B Biol Sci. 1978;203(1152):305–21.PubMedCrossRef Parry DA, Barnes GR, Craig AS. A comparison of the size distribution of collagen fibrils in connective tissues as a function of age and a possible relation between fibril size distribution and mechanical properties. Proc R Soc Lond B Biol Sci. 1978;203(1152):305–21.PubMedCrossRef
50.
Zurück zum Zitat Nakagawa Y, Majima T, Nagashima K. Effect of ageing on ultrastructure of slow and fast skeletal muscle tendon in rabbit Achilles tendons. Acta Physiol Scand. 1994;152(3):307–13.PubMedCrossRef Nakagawa Y, Majima T, Nagashima K. Effect of ageing on ultrastructure of slow and fast skeletal muscle tendon in rabbit Achilles tendons. Acta Physiol Scand. 1994;152(3):307–13.PubMedCrossRef
51.
Zurück zum Zitat Longo UG, Ronga M, Maffulli N. Acute ruptures of the achilles tendon. Sports Med Arthrosc. 2009;17(2):127–38.PubMedCrossRef Longo UG, Ronga M, Maffulli N. Acute ruptures of the achilles tendon. Sports Med Arthrosc. 2009;17(2):127–38.PubMedCrossRef
52.
Zurück zum Zitat Shakibaei M, Pfister K, Schwabe R, Vormann J, Stahlmann R. Ultrastructure of Achilles tendons of rats treated with ofloxacin and fed a normal or magnesium-deficient diet. Antimicrob Agents Chemother. 2000;44(2):261–6.PubMedCrossRefPubMedCentral Shakibaei M, Pfister K, Schwabe R, Vormann J, Stahlmann R. Ultrastructure of Achilles tendons of rats treated with ofloxacin and fed a normal or magnesium-deficient diet. Antimicrob Agents Chemother. 2000;44(2):261–6.PubMedCrossRefPubMedCentral
53.
Zurück zum Zitat Jorgensen C, Anaya JM, Didry C, Canovas F, Serre I, Baldet P, et al. [Arthropathy with achilles tendon involvement induced by pefloxacin. Apropos of a case] Arthropathies et tendinopathie achilleenne induites par la pefloxacine. A propos d’une observation. Rev Rhum Mal Osteoartic. 1991;58(9):623–5.PubMed Jorgensen C, Anaya JM, Didry C, Canovas F, Serre I, Baldet P, et al. [Arthropathy with achilles tendon involvement induced by pefloxacin. Apropos of a case] Arthropathies et tendinopathie achilleenne induites par la pefloxacine. A propos d’une observation. Rev Rhum Mal Osteoartic. 1991;58(9):623–5.PubMed
54.
Zurück zum Zitat Movin T, Gad A, Guntner P, Foldhazy Z, Rolf C. Pathology of the Achilles tendon in association with ciprofloxacin treatment. Foot Ankle Int. 1997;18(5):297–9.PubMedCrossRef Movin T, Gad A, Guntner P, Foldhazy Z, Rolf C. Pathology of the Achilles tendon in association with ciprofloxacin treatment. Foot Ankle Int. 1997;18(5):297–9.PubMedCrossRef
55.
Zurück zum Zitat Sendzik J, Shakibaei M, Schafer-Korting M, Stahlmann R. Fluoroquinolones cause changes in extracellular matrix, signalling proteins, metalloproteinases and caspase-3 in cultured human tendon cells. Toxicology. 2005;212(1):24–36.PubMedCrossRef Sendzik J, Shakibaei M, Schafer-Korting M, Stahlmann R. Fluoroquinolones cause changes in extracellular matrix, signalling proteins, metalloproteinases and caspase-3 in cultured human tendon cells. Toxicology. 2005;212(1):24–36.PubMedCrossRef
56.
Zurück zum Zitat Jarvinen TA, Kannus P, Paavola M, Jarvinen TL, Jozsa L, Jarvinen M. Achilles tendon injuries. Curr Opin Rheumatol. 2001;13(2):150–5.PubMedCrossRef Jarvinen TA, Kannus P, Paavola M, Jarvinen TL, Jozsa L, Jarvinen M. Achilles tendon injuries. Curr Opin Rheumatol. 2001;13(2):150–5.PubMedCrossRef
57.
Zurück zum Zitat Jones JG. Achilles tendon rupture following steroid injection. J Bone Joint Surg Am. 1985;67(1):170.PubMed Jones JG. Achilles tendon rupture following steroid injection. J Bone Joint Surg Am. 1985;67(1):170.PubMed
58.
Zurück zum Zitat Smith M, Simpson NE. Report of the committee on the genetic constitution of 9 and 10. Cytogenet Cell Genet. 1989;51(1–4):202–25.PubMedCrossRef Smith M, Simpson NE. Report of the committee on the genetic constitution of 9 and 10. Cytogenet Cell Genet. 1989;51(1–4):202–25.PubMedCrossRef
59.
Zurück zum Zitat Samiric T, Ilic MZ, Handley CJ. Characterisation of proteoglycans and their catabolic products in tendon and explant cultures of tendon. Matrix Biol. 2004;23(2):127–40.PubMedCrossRef Samiric T, Ilic MZ, Handley CJ. Characterisation of proteoglycans and their catabolic products in tendon and explant cultures of tendon. Matrix Biol. 2004;23(2):127–40.PubMedCrossRef
60.
Zurück zum Zitat Corps AN, Robinson AH, Movin T, Costa ML, Ireland DC, Hazleman BL, et al. Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies. Rheumatology (Oxford). 2004;43(8):969–72.PubMedCrossRef Corps AN, Robinson AH, Movin T, Costa ML, Ireland DC, Hazleman BL, et al. Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies. Rheumatology (Oxford). 2004;43(8):969–72.PubMedCrossRef
61.
Zurück zum Zitat Scott A, Lian O, Bahr R, Hart DA, Duronio V. VEGF expression in patellar tendinopathy: a preliminary study. Clin Orthop Relat Res. 2008;466(7):1598–604.PubMedCrossRefPubMedCentral Scott A, Lian O, Bahr R, Hart DA, Duronio V. VEGF expression in patellar tendinopathy: a preliminary study. Clin Orthop Relat Res. 2008;466(7):1598–604.PubMedCrossRefPubMedCentral
62.
Zurück zum Zitat Wang JH, Jia F, Yang G, Yang S, Campbell BH, Stone D, et al. Cyclic mechanical stretching of human tendon fibroblasts increases the production of prostaglandin E2 and levels of cyclooxygenase expression: a novel in vitro model study. Connect Tissue Res. 2003;44(3–4):128–33.PubMedCrossRef Wang JH, Jia F, Yang G, Yang S, Campbell BH, Stone D, et al. Cyclic mechanical stretching of human tendon fibroblasts increases the production of prostaglandin E2 and levels of cyclooxygenase expression: a novel in vitro model study. Connect Tissue Res. 2003;44(3–4):128–33.PubMedCrossRef
63.
Zurück zum Zitat Hui W, Bell M, Carroll G. Oncostatin M (OSM) stimulates resorption and inhibits synthesis of proteoglycan in porcine articular cartilage explants. Cytokine. 1996;8(6):495–500.PubMedCrossRef Hui W, Bell M, Carroll G. Oncostatin M (OSM) stimulates resorption and inhibits synthesis of proteoglycan in porcine articular cartilage explants. Cytokine. 1996;8(6):495–500.PubMedCrossRef
Metadaten
Titel
Predictors of Primary Achilles Tendon Ruptures
verfasst von
Femke M. A. P. Claessen
Robert-Jan de Vos
Max Reijman
Duncan E. Meuffels
Publikationsdatum
01.09.2014
Verlag
Springer International Publishing
Erschienen in
Sports Medicine / Ausgabe 9/2014
Print ISSN: 0112-1642
Elektronische ISSN: 1179-2035
DOI
https://doi.org/10.1007/s40279-014-0200-z

Weitere Artikel der Ausgabe 9/2014

Sports Medicine 9/2014 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.