Skip to main content
Erschienen in: Journal of Endocrinological Investigation 7/2020

01.07.2020 | Comment

COVID-19 and the endocrine system: exploring the unexplored

verfasst von: R. Pal, M. Banerjee

Erschienen in: Journal of Endocrinological Investigation | Ausgabe 7/2020

Einloggen, um Zugang zu erhalten

Excerpt

A novel coronavirus disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected over 2.3 million people, claiming more than 160000 lives in over 200 countries worldwide. Although COVID-19 can be asymptomatic, the primary presentation in symptomatic patients is in the form of viral pneumonia, sometimes complicated by acute respiratory distress syndrome and/or sepsis. In addition, myocarditis and acute kidney injury have also been described in COVID-19. On the contrary, endocrinological manifestations have not yet been reported in patients with COVID-19. …
Literatur
3.
Zurück zum Zitat Yang JK, Feng Y, Yuan MY, Yuan SY, Fu HJ, Wu BY et al (2006) Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS. Diabet Med 23:623–628CrossRef Yang JK, Feng Y, Yuan MY, Yuan SY, Fu HJ, Wu BY et al (2006) Plasma glucose levels and diabetes are independent predictors for mortality and morbidity in patients with SARS. Diabet Med 23:623–628CrossRef
4.
Zurück zum Zitat Yang J-K, Lin S-S, Ji X-J, Guo L-M (2010) Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes. Acta Diabetol 47:193–199CrossRef Yang J-K, Lin S-S, Ji X-J, Guo L-M (2010) Binding of SARS coronavirus to its receptor damages islets and causes acute diabetes. Acta Diabetol 47:193–199CrossRef
5.
Zurück zum Zitat Ding Y, He L, Zhang Q, Huang Z, Che X, Hou J et al (2004) Organ distribution of severe acute respiratory syndrome(SARS) associated coronavirus(SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways. J Pathol 203:622–630CrossRef Ding Y, He L, Zhang Q, Huang Z, Che X, Hou J et al (2004) Organ distribution of severe acute respiratory syndrome(SARS) associated coronavirus(SARS-CoV) in SARS patients: implications for pathogenesis and virus transmission pathways. J Pathol 203:622–630CrossRef
6.
Zurück zum Zitat Jaeckel E, Manns M, Herrath M (2006) Viruses and diabetes. Ann N Y Acad Sci 958:7–25CrossRef Jaeckel E, Manns M, Herrath M (2006) Viruses and diabetes. Ann N Y Acad Sci 958:7–25CrossRef
7.
Zurück zum Zitat Wan J, Sun W, Li X, Ying W, Dai J, Kuai X et al (2006) Inflammation inhibitors were remarkably up-regulated in plasma of severe acute respiratory syndrome patients at progressive phase. Proteomics 6:2886–2894CrossRef Wan J, Sun W, Li X, Ying W, Dai J, Kuai X et al (2006) Inflammation inhibitors were remarkably up-regulated in plasma of severe acute respiratory syndrome patients at progressive phase. Proteomics 6:2886–2894CrossRef
8.
Zurück zum Zitat Pal R, Bhansali A (2020) COVID-19, diabetes mellitus and ACE2: the conundrum. Diabetes Res Clin Pract 162:108132CrossRef Pal R, Bhansali A (2020) COVID-19, diabetes mellitus and ACE2: the conundrum. Diabetes Res Clin Pract 162:108132CrossRef
9.
Zurück zum Zitat Guo W, Li M, Dong Y, Zhou H, Zhang Z, Tian C et al (2020) Diabetes is a risk factor for the progression and prognosis of COVID-19. Diabetes Metab Res Rev 7:e3319CrossRef Guo W, Li M, Dong Y, Zhou H, Zhang Z, Tian C et al (2020) Diabetes is a risk factor for the progression and prognosis of COVID-19. Diabetes Metab Res Rev 7:e3319CrossRef
11.
Zurück zum Zitat Zhang W, Xu Y-Z, Liu B, Wu R, Yang Y-Y, Xiao X-Q et al (2014) Pioglitazone upregulates angiotensin converting enzyme 2 expression in insulin-sensitive tissues in rats with high-fat diet-induced nonalcoholic steatohepatitis. Sci World J 2014:1–7 Zhang W, Xu Y-Z, Liu B, Wu R, Yang Y-Y, Xiao X-Q et al (2014) Pioglitazone upregulates angiotensin converting enzyme 2 expression in insulin-sensitive tissues in rats with high-fat diet-induced nonalcoholic steatohepatitis. Sci World J 2014:1–7
12.
Zurück zum Zitat Romaní-Pérez M, Outeiriño-Iglesias V, Moya CM, Santisteban P, González-Matías LC, Vigo E et al (2015) Activation of the GLP-1 receptor by liraglutide increases ACE2 expression, reversing right ventricle hypertrophy, and improving the production of SP-A and SP-B in the lungs of type 1 diabetes rats. Endocrinology 156:3559–3569CrossRef Romaní-Pérez M, Outeiriño-Iglesias V, Moya CM, Santisteban P, González-Matías LC, Vigo E et al (2015) Activation of the GLP-1 receptor by liraglutide increases ACE2 expression, reversing right ventricle hypertrophy, and improving the production of SP-A and SP-B in the lungs of type 1 diabetes rats. Endocrinology 156:3559–3569CrossRef
13.
Zurück zum Zitat Pal R, Bhadada SK (2020) Should anti-diabetic medications be reconsidered amid COVID-19 pandemic? Diabetes Res Clin Pract 163:108146CrossRef Pal R, Bhadada SK (2020) Should anti-diabetic medications be reconsidered amid COVID-19 pandemic? Diabetes Res Clin Pract 163:108146CrossRef
15.
Zurück zum Zitat Richard C, Wadowski M, Goruk S, Cameron L, Sharma AM, Field CJ (2017) Individuals with obesity and type 2 diabetes have additional immune dysfunction compared with obese individuals who are metabolically healthy. BMJ Open Diabetes Res Care 5:e000379CrossRef Richard C, Wadowski M, Goruk S, Cameron L, Sharma AM, Field CJ (2017) Individuals with obesity and type 2 diabetes have additional immune dysfunction compared with obese individuals who are metabolically healthy. BMJ Open Diabetes Res Care 5:e000379CrossRef
16.
Zurück zum Zitat Sanyal D, Raychaudhuri M (2016) Hypothyroidism and obesity: an intriguing link. Indian J Endocrinol Metab 20:554CrossRef Sanyal D, Raychaudhuri M (2016) Hypothyroidism and obesity: an intriguing link. Indian J Endocrinol Metab 20:554CrossRef
17.
Zurück zum Zitat Fernandez CJ, Chacko EC, Pappachan JM (2019) Male obesity-related secondary hypogonadism—pathophysiology. Clinical Implications and Management. Eur Endocrinol 15:83CrossRef Fernandez CJ, Chacko EC, Pappachan JM (2019) Male obesity-related secondary hypogonadism—pathophysiology. Clinical Implications and Management. Eur Endocrinol 15:83CrossRef
19.
Zurück zum Zitat Xu J, Qi L, Chi X, Yang J, Wei X, Gong E et al (2006) Orchitis: a complication of severe acute respiratory syndrome (SARS)1. Biol Reprod 74:410–416CrossRef Xu J, Qi L, Chi X, Yang J, Wei X, Gong E et al (2006) Orchitis: a complication of severe acute respiratory syndrome (SARS)1. Biol Reprod 74:410–416CrossRef
20.
Zurück zum Zitat Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S (2017) Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection. J Immunol 198:4046–4053CrossRef Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S (2017) Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection. J Immunol 198:4046–4053CrossRef
21.
Zurück zum Zitat Wheatland R (2004) Molecular mimicry of ACTH in SARS—implications for corticosteroid treatment and prophylaxis. Med Hypotheses 63:855–862CrossRef Wheatland R (2004) Molecular mimicry of ACTH in SARS—implications for corticosteroid treatment and prophylaxis. Med Hypotheses 63:855–862CrossRef
22.
Zurück zum Zitat Xu J, Zhao S, Teng T, Abdalla AE, Zhu W, Xie L et al (2020) Systematic comparison of two animal-to-human transmitted human coronaviruses: SARS-CoV-2 and SARS-CoV. Viruses 12:244CrossRef Xu J, Zhao S, Teng T, Abdalla AE, Zhu W, Xie L et al (2020) Systematic comparison of two animal-to-human transmitted human coronaviruses: SARS-CoV-2 and SARS-CoV. Viruses 12:244CrossRef
25.
Zurück zum Zitat Leow MK-S, Kwek DS-K, Ng AW-K, Ong K-C, Kaw GJ-L, Lee LS-U (2005) Hypocortisolism in survivors of severe acute respiratory syndrome (SARS). Clin Endocrinol (Oxf) 63:197–202CrossRef Leow MK-S, Kwek DS-K, Ng AW-K, Ong K-C, Kaw GJ-L, Lee LS-U (2005) Hypocortisolism in survivors of severe acute respiratory syndrome (SARS). Clin Endocrinol (Oxf) 63:197–202CrossRef
27.
Zurück zum Zitat De Jongh F, Jobsis A, Elte J (2001) Thyroid morphology in lethal non-thyroidal illness: a post-mortem study. Eur J Endocrinol 144:221–226CrossRef De Jongh F, Jobsis A, Elte J (2001) Thyroid morphology in lethal non-thyroidal illness: a post-mortem study. Eur J Endocrinol 144:221–226CrossRef
28.
Zurück zum Zitat Wei L, Sun S, Xu C, Zhang J, Xu Y, Zhu H et al (2007) Pathology of the thyroid in severe acute respiratory syndrome. Hum Pathol 38:95–102CrossRef Wei L, Sun S, Xu C, Zhang J, Xu Y, Zhu H et al (2007) Pathology of the thyroid in severe acute respiratory syndrome. Hum Pathol 38:95–102CrossRef
Metadaten
Titel
COVID-19 and the endocrine system: exploring the unexplored
verfasst von
R. Pal
M. Banerjee
Publikationsdatum
01.07.2020
Verlag
Springer International Publishing
Erschienen in
Journal of Endocrinological Investigation / Ausgabe 7/2020
Elektronische ISSN: 1720-8386
DOI
https://doi.org/10.1007/s40618-020-01276-8

Weitere Artikel der Ausgabe 7/2020

Journal of Endocrinological Investigation 7/2020 Zur Ausgabe

Leitlinien kompakt für die Innere Medizin

Mit medbee Pocketcards sicher entscheiden.

Seit 2022 gehört die medbee GmbH zum Springer Medizin Verlag

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.