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Horse-meat allergy mediated by dog-allergy: a case report and review of the literature

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Abstract

The pork-cat syndrome is an IgE-mediated allergy to pork triggered by a primary sensitization to cat dander. IgE-antibodies are directed to cat serum albumin, Fel d 2, and cross-react with porcine serum albumin. In contrast to meat anaphylaxis caused by IgE to α-Gal, in patients with pork-cat syndrome, symptoms occur in less than two hours after consumption. As albumin is a thermolabile allergen, patients often tolerate well done meat. In this review, different allergens of red meat are described and an original case of allergy to horse meat mediated by allergy to dog dander is presented.

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Abbreviations

ELISA:

Enzyme-linked immunosorbent assay

Ig:

Immunoglobulin

RAST:

Radioallergosorbent test

SA:

Serum albumin

SDS-PAGE:

Sodium dodecylsulfate polyacrylamide gel electrophoresis

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Correspondence to Martine Morisset MD, PhD.

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The authors declare no conflict of interest.

Acknowledgment

The present work has been funded by the Ministry of Higher Education and Research in Luxembourg.

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Morisset M, Arumugam K, Ollert M, Hilger C. Horse-meat allergy mediated by dog-allergy: a case report and review of the literature. Allergo J Int 2016; 25:76–81 DOI: 10.1007/s40629-016-0103-7

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Morisset, M., Arumugam, K., Ollert, M. et al. Horse-meat allergy mediated by dog-allergy: a case report and review of the literature. Allergo J Int 25, 76–81 (2016). https://doi.org/10.1007/s40629-016-0109-1

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