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A century of “intrinsic asthma”

A view on the development of phenotyping in asthma in the last 100 years

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Abstract

Background

One hundred years ago Rackemann published the first description of Intrinsic Asthma. This was the beginning of a process of phenotyping the disease.

Materials and methods

The literature regarding asthma phenotypes of the last 100 years has been checked. Lately, there have been many new publications dealing with this specific asthma phenotype.

Conclusion

Today, the term asthma is looked at as an umbrella covering different phenotypes of the disease. According to a recent publication, Intrinsic Asthma is most often cited now as eosinophilic adult-onset asthma. New treatment strategies for this phenotypes have evolved in recent years.

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Authors and Affiliations

  1. Pneumologie, Kantonsspital Graubünden, Loestr. 100, 7000, Chur, Switzerland

    Thomas Rothe M.D.

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  1. Thomas Rothe M.D.
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Correspondence to Thomas Rothe M.D..

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Conflict of interest

T. Rothe gave advice and has given lectures for: AstraZeneca, GSK, TEVA, and Novartis Pharma Schweiz.

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Rothe, T. A century of “intrinsic asthma”. Allergo J Int 27, 215–219 (2018). https://doi.org/10.1007/s40629-018-0051-5

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  • DOI: https://doi.org/10.1007/s40629-018-0051-5

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