Myocardial disarray at junction of ventricular septum and left and right ventricular free walls in hypertrophic cardiomyopathy
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Cited by (127)
Cardiac structure discontinuities revealed by ex-vivo microstructural characterization. A focus on the basal inferoseptal left ventricle region
2023, Journal of Cardiovascular Magnetic ResonanceIdentification of Myocardial Disarray in Patients With Hypertrophic Cardiomyopathy and Ventricular Arrhythmias
2019, Journal of the American College of CardiologyCitation Excerpt :This matched the ring of coherently aligned circumferentially orientated myocytes revealed on the HA map and in published histology (Central Illustration panel E) (13–15). By contrast, this mid-wall ring was disrupted in HCM at the anterior junction and the hypertrophied anteroseptum (Central Illustration panels B and C), and in some cases, the ring was absent (Central Illustration panel D), again consistent with patterns seen in published HCM histology (Central Illustration panel E) (14). Areas of profoundly low FA matched the regions of LGE and elevated ECV (Central Illustration panel C), in line with fibrosis contributing to low FA, but low FA could not be explained by fibrosis in all cases.
Anatomy, Function, and Dysfunction of the Right Ventricle: JACC State-of-the-Art Review
2019, Journal of the American College of CardiologyPredictors of future onset of atrial fibrillation in hypertrophic cardiomyopathy
2018, Archives of Cardiovascular DiseasesCitation Excerpt :Interestingly, the pattern of fibrosis on LV-RV junctions was the one most closely related to future AF development. In HCM patients, RV insertion points are a common site of LGE on CMR [30], as well as a common site of plexiform fibrosis and myocardial disarray on histopathology [31]. However, this finding is not specific to HCM [32].
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Dr. Kuribayashi was supported in part by Meiji Institute of Health Science, Odawara, Japan.