Elsevier

Biological Psychiatry

Volume 39, Issue 12, 15 June 1996, Pages 1032-1038
Biological Psychiatry

Blink rate in children with attention-deficit-hyperactivity disorder

https://doi.org/10.1016/0006-3223(95)00315-0Get rights and content

Spontaneous blink rate, a noninvasive measure of dopamine function, was coded in 28 children with attention-deficit-hyperactivity disorder (ADHD) and in 47 normal children during a listening, a conversation, and a verbal recall task. Unlike the normal children, the children with ADHD did not increase their blink rates significantly across these three tasks. The ADHD subjects who were not on stimulants had significantly lower blink rates than the normal children during verbal recall. The ADHD subjects on stimulants, however, had significantly higher blink rates than the normal subjects during the listening task. These preliminary findings are discussed in light of their potential implications for theories on neurotransmitter dysfunction and arousal in ADHD.

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    This study was supported in part by National Institute of Mental Health grant KO1-MH00538 and NIMH R37 MH-45112.

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