Main articleEffects of focused selective attention tasks on event-related potentials in autistic and normal individuals☆
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2019, Clinical NeurophysiologyCitation Excerpt :The paradigm is an extended version of the well-established oddball paradigm (Squires et al., 1975), which measures P3b and cognitive processes associated with target detection (Squires et al., 1976; Donchin and Coles, 1988; Poulsen et al., 2005; Polich and Criado, 2006; Fogelson, 2015). Attenuated P3b amplitudes have been observed in subjects with ASD (Courchesne et al., 1989; Ciesielski et al., 1990; Salmond et al., 2007; Duncan et al., 2009; Maekawa et al., 2011). In the current study, we evaluated the ability of ASD subjects to detect different target conditions (random and predictable targets) and to process goal-directed information (a predictive sequence).
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The research was supported by NIMH Grant 1-R01-MH36840 and NINCDS Grant 5-R01-NS19855 awarded to E. Courchesne; and by grants from Children's Hospital Research Center, San Diego, and the School of Medicine, University of Alberta awarded to K.T. Ciesielski.
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Thanks are sent to Natacha Akshoomoff for her assistance in data analysis and to Marta Kutas and Steven A. Hillyard for consultations.