The International Journal of Applied Radiation and Isotopes
Volume 36, Issue 12, December 1985, Pages 1003-1004
preliminary communicationRadioiodination and preliminary in vivo investigation of the alkaloid cryptolepine
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Cited by (3)
Pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria
2013, Acta TropicaCitation Excerpt :Contrary to the earlier studies; cryptolepine persisted in blood up to 10 h following administration. That observation could be due to prolonged absorption from the gastrointestinal tract as well as enterohepatic circulation as suggested by Salako et al. (1985). Although the above studies provided very useful information on the pharmacokinetics of the compound, it is important that when the compound is incorporated into a dosage form, the in vivo profile be reinvestigated.
In vitro anti-malarial interaction and gametocytocidal activity of cryptolepine
2017, Malaria JournalIdentification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats
2017, BMC Pharmacology and Toxicology
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