The effect of disodium cromoglycate on the release of histamine and degranulation of rat mast cells induced by compound
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Cited by (81)
Mast cell stabilisers
2016, European Journal of PharmacologyCitation Excerpt :In 1967, following fortuitous studies on compounds with structural similarity to khellin, cromolyn sodium was launched as the first of a new therapeutical class, the mast cell stabilisers (Altounyan, 1967). Cromolyn sodium can inhibit both passive cutaneous anaphylaxis (PCA) in the rat and the release of histamine from rat peritoneal cells induced by Compound 48/80 (Orr et al., 1971). Using enzymatic and mechanical methods of dispersion, Church et al. demonstrated that cromolyn sodium and similar antiallergic drugs caused weak inhibition (<35% at 100–1000 μM) of histamine release from human lung cells, although all antiallergic drugs tested, unlike the more potent beta agonist, salbutamol, showed rapid development of tachyphlaxis (Church and Gradidge, 1980).
Mast cell stabilising activity of Bacopa monnieri
2001, FitoterapiaComparative effects of topical ocular anti-allergy drugs on human conjunctival mast cells
1997, Annals of Allergy, Asthma and ImmunologyCharacterization of the 78 kDa mast cell protein phosphorylated by the antiallergic drug cromolyn and homology to moesin
1996, Biochemical PharmacologyCharacterization of Gastric Mucosal Blood Flow Response Induced by Intragastric Capsaicin in Rats
1991, The Japanese Journal of PharmacologyAmelioration of 4′-epidoxorubicin-induced cardiotoxicity by sodium cromoglycate
1989, European Journal of Cancer and Clinical Oncology