Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Volume 247, Issue 2, April 1991, Pages 267-281
Role of genetics and drug metabolism in human cancer risk
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Cited by (239)
Polymorphism of CYP1A1 gene variants rs4646903 and rs1048943 relation to the incidence of cervical cancer in Chhattisgarh
2017, Environmental Toxicology and PharmacologyCitation Excerpt :CYP1A1 enzyme is also conscientious for aryl hydrocarbon hydroxylase activity of widespread environmental carcinogens like polyaromatic hydrocarbon, polyaromatic amines, dibenzofurans and biphenyls. Due to the altered CYP1A1 enzyme activity, the substance causes cell damage by forming cell adducts, damage lipids and proteins too (Nebert, 1991). The CYP1A1 gene is present on chromosome 15q22-24 possessing 5987 bp encoding a protein of 512 amino acids (Sowers et al., 2006).
Protein expression of CYP1A1, CYP1B1, ALDH1A1, and ALDH2 in young patients with oral squamous cell carcinoma
2016, International Journal of Oral and Maxillofacial SurgeryAssociation of CYP1A1 gene variants rs4646903 (T>C) and rs1048943 (A>G) with cervical cancer in a North Indian population
2014, European Journal of Obstetrics and Gynecology and Reproductive BiologyUsing gene-environment interaction analyses to clarify the role of well-done meat and heterocyclic amine exposure in the etiology of colorectal polyps
2012, American Journal of Clinical Nutrition
Copyright © 1991 Published by Elsevier B.V.