Panel reportIs pelvic radiation beneficial in the postoperative management of stage Ib squamous cell carcinoma of the cervix with pelvic node metastasis treated by radical hysterectomy and pelvic lymphadenectomy?: A report from the presidential panel at the 1979 Annual Meeting of the Society of Gynecologic Oncologists
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Cited by (193)
Invasive cervical cancer
2023, DiSaia and Creasman Clinical Gynecologic OncologyPostoperative radiation rates in stage IIA1 cervical cancer: Is surgical treatment justified? An Israeli Gynecologic Oncology Group Study
2018, Gynecologic OncologyCitation Excerpt :Despite attempts at risk stratification to select patients with early cervical cancer for surgical treatment, a wide range of post-operative radiation 9.9%–68% has been reported, depending on the indications used to guide management [3,8,17–19]. Adjuvant therapy is indicated in cases with lymph nodes metastases, positive or close resection margins, or parametrial involvement, where recurrence rates are high [19–27] and where the use of radiotherapy may reduce the risk of recurrence [3,4,6,28,29]. Other risk factors for recurrence include depth of stromal invasion, LVSI, and tumor size [18,20,30–32]; postoperative radiation has been shown to improve outcome for patients with a combination of these “intermediate” risk factors [5,33] and is recommended in the NCCN guidelines [1] but is somewhat controversial [24,34].
Invasive cervical cancer
2018, Clinical Gynecologic OncologyInvasive Cervical Cancer
2012, Clinical Gynecologic Oncology: Eighth EditionSurgical treatment of lymph node metastases in stage IB cervical cancer. the laterally extended parametrectomy (LEP) procedure: Experience with a 5 year follow-up
2011, Gynecologic OncologyCitation Excerpt :This phenomenon has initiated the routine use of adjuvant pelvic radiotherapy in patients with pelvic nodal metastases. However, nonrandomized retrospective studies have not demonstrated a survival advantage for adjuvant radiotherapy in this group of patients [10,11]. Burghardt et al., Benedetti-Panici et al., Girardi et al. have all documented the location of parametrial lymph nodes, and found them to be randomly distributed, with an equal number of metastatic parametrial lymph nodes in the lateral and medial parametria [13–16].
Primary surgery versus chemoradiation in the treatment of IB2 cervical carcinoma: A cost effectiveness analysis
2007, Gynecologic OncologyCitation Excerpt :Since then, gynecologic and radiation oncologists have attempted to define the optimal treatment strategy for patients with stage IB2 disease. Prospective and retrospective studies report approximately equal rates of cure for stage IB cervical cancer using primary radiotherapy or radical hysterectomy [2–5]. However, over the past 10 years, the addition of platinum-based chemotherapy to radiotherapy in the primary or adjuvant treatment setting has reduced recurrence rates and improved overall survival [6–10].
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