Cell
Volume 11, Issue 4, August 1977, Pages 719-727
Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle
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Cited by (230)
Mitochondrial DNA is a major source of driver mutations in cancer
2022, Trends in CancerDdCBE mediates efficient and inheritable modifications in mouse mitochondrial genome
2022, Molecular Therapy Nucleic AcidsCitation Excerpt :An independent mitochondrial genome (mtDNA) that encodes 37 genes is also of great importance. The double-stranded and circular mtDNA is continuously turned over, independently of the nuclear genome.7 Since the first pathogenic mtDNA mutation was identified in 1988,8,9 over 250 mtDNA mutations (point mutation and rearrangement) have been characterized and connected with human diseases.10–14
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