Anatomoclinical correlations of the aphasias as defined through computerized tomography: Exceptions☆
References (46)
- et al.
Pattern of recovery of oral and written expression and comprehension in aphasic patients
Behavioral Brain Research
(1982) Fluency in aphasia: Correlation with radioactive scan localization
Cortex
(1967)- et al.
Transcortical features of aphasia following left thalamic hemorrhage
Cortex
(1979) - et al.
Normative data and screening power of a shortened version of the Token Test
Cortex
(1978) - et al.
The fluency—non fluency dimension in aphasia
Cortex
(1972) - et al.
Computer tomographic localization, lesion size, and prognosis in aphasia and nonverbal impairment
Brain and Language
(1979) - et al.
Speech fluency in aphasics
Brain and Language
(1980) - et al.
Paroxysmal aphasia
Brain and Language
(1980) - et al.
Unexpected anatomical findings in a case of fluent jargon aphasia
Cortex
(1973) - et al.
Further suggestions for cerebral CT-localization
Cortex
(1979)
Language localization and variability
Brain and Language
The assessment and analysis of handedness: The Edinburgh Inventory
Neuropsychologia
Recovery from aphasia: Spontaneus speech versus language comprehension
Brain and Language
Spontaneous speech of aphasic patients: A psycholinguistic analysis
Brain and Language
Clinical aspects of dysphasia
Troubles du langage de type aphasique et lésions putamino-caudées
Observations anatomocliniques
Revue Neurologique
Is ideomotor apraxia the outcome of damage to well-defined regions of the left hemisphere?
Journal of Neurology, Neurosurgery and Psychiatry
A refined method to relate morphological and functional aspects of aphasia
European Neurology
Hémorragie de la tête du noyau caudé gauche
Revue Neurologique
Brain specialization for language does not depend on literacy
Archives of Neurology
The anatomical basis of conduction aphasia
Brain
Untersuchungen über die Lokalisation der Funktionen in der Grosshirnrinde des Menschen
Zur Auffasung der Aphasien
Cited by (167)
Lesion-symptom mapping: From single cases to the human disconnectome
2021, Encyclopedia of Behavioral Neuroscience: Second EditionNeural reuse of action perception circuits for language, concepts and communication
2018, Progress in NeurobiologyCitation Excerpt :In this sense, the perisylvian language cortex includes the posterior inferior frontal area named after Broca (Brodmann areas, BA, 44, 45) along with the superior temporal cortex (BA 42, 22) sometimes considered Wernicke’s region, plus further adjacent sites in inferior frontal, parietal and temporal cortex. Substantial lesions in the left perisylvian language cortex typically cause aphasia affecting both production and comprehension of language (Bates et al., 2003; Rosenbek et al., 1995); this general rule holds for most right- and the majority of left-handers, although exceptions from it are well-known (Basso et al., 1985). Although a wide range of cortical areas in both hemispheres along with subcortical sites are relevant for language, and especially for semantic-conceptual processing (see especially Section 3.2), the structure and function of a core part of the perisylvian areas in frontal and temporal cortex may be of special importance to the understanding of language mechanisms.
The unbridged gap between clinical diagnosis and contemporary research on aphasia: A short discussion on the validity and clinical utility of taxonomic categories
2017, Brain and LanguageCitation Excerpt :In addition to the above limitations, there are widely reported inconsistencies with regard to the predicted lesion-to-syndrome correspondence. Basso, Lecours, Moraschini, and Vanier (1985) reported an extensive series of such cases: global aphasia in the presence of an intact Wernicke’s area, Wernicke’s aphasia after extended perisylvian lesions, fluent aphasia after anterior lesions, nonfluent aphasia after posterior lesions, and aphasia resulting from lesions outside the perisylvian language zone. There is also a plethora of single-case reports which present massive left-lateralized lesions associated with non-expected syndromes, similar lesions resulting in different symptomatology, as well as crossed non-aphasia phenomena (for a review, see Charidimou et al., 2014).
Using principal component analysis to capture individual differences within a unified neuropsychological model of chronic post-stroke aphasia: Revealing the unique neural correlates of speech fluency, phonology and semantics
2017, CortexCitation Excerpt :Furthermore, when these have been considered, they have been investigated separately and thus the inter-relationship between them is unclear (e.g., is speech fluency, in part, a reflection of patients' phonological or semantic skills?). Classically, damage to left frontal areas was associated with poor fluency (Broca, 1861); however, studies using high-resolution Magnetic Resonance Imaging (MRI) techniques have found that left frontal lesions do not always result in Broca's aphasia (Basso, Lecours, Moraschini, & Vanier, 1985; Willmes & Poeck, 1993) and production deficits can occur following lesions outside of the frontal lobe, including white matter tracts and the anterior insula (aINS) (Bates et al., 2003; Blank, Scott, Murphy, Warburton, & Wise, 2002; Damasio, 1992; Dronkers, 1996; Mohr et al., 1978; Wise, Greene, Büchel, & Scott, 1999). Functional neuroimaging studies have identified a broader neural network during connected-speech production.
Syntactic processing is distributed across the language system
2016, NeuroImageCitation Excerpt :On the one hand, investigations of patients with brain damage have revealed that lesions to many different parts of the language system can cause similar syntactic comprehension difficulties. Such regions include Broca's region in the inferior frontal gyrus (e.g., Caramazza and Zurif, 1976; Schwartz et al., 1980; Caplan and Futter, 1986; Zurif et al., 1993; Grodzinsky, 2000), the arcuate fasciculus and/or the extreme capsule (e.g., Caramazza and Zurif, 1976; Papoutsi et al., 2011; Rolheiser, Stamatakis, and Tyler, 2011; Tyler et al., 2011; Wilson et al., 2011), posterior temporal regions (e.g., Samuels and Benson, 1979; Selnes et al., 1983; Basso et al., 1985; Tramo et al., 1988; Caplan et al., 1996; Bastiaanse and Edwards, 2004; Wilson and Saygin, 2004; Amici et al., 2007; Tyler et al., 2011; Thothathiri et al., 2012), and anterior temporal regions (e.g., Dronkers et al., 1994; Dronkers et al., 2004; Magnusdottir et al., 2013). For instance, lesions in all of these regions can impair the interpretation of semantically reversible sentences, such as The boy is chased by the girl, whose meanings (who did what to whom) depend on their syntactic form (i.e., word order, function words, and functional morphology).
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Supported by Grant PG-28 from the Conseil de la Recherche Médicale du Canada.