PaperThe in vitro response of osteoblasts to bioactive glass
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Cited by (135)
Optimization of poly (lactic-co-glycolic acid)-bioactive glass composite scaffold for bone tissue engineering using stem cells from human exfoliated deciduous teeth
2021, Archives of Oral BiologyCitation Excerpt :The scaffold containing bioactive glass showed higher ALP staining than the scaffold with PLGA alone. Several studies have reported that bioactive glass induces osteoblast production and new bone formation by releasing Ca, P, and Si from the scaffold into the matrix, which stimulates ALP expression (Effah Kaufmann, Ducheyne, & Shapiro, 2000; Matsuda & Davies, 1987; Price, Bendall, Frondoza, Jinnah, & Hungerford, 1997). Moreover, PLGA-bioactive glass composite scaffolds showed higher expression of Osterix, Runt-related transcription factor 2, collagen type I, osteonectin, and osteocalcin, which are essential genes for bone formation, compared to the PLGA scaffold.
Fine analysis of interaction mechanism of bioactive glass surface after soaking in SBF solution: AFM and ICP-OES investigations
2020, Applied Surface ScienceCitation Excerpt :The SiOSi bending signal at 465 cm−1 and 1230 cm−1 in relation with phosphate groups vibrations at 1100 cm−1 and 585 cm−1 and finally the Ca presence confirmed by the vibration bands at 800 cm−1 assigned at SiOCa with non-linking oxygen. The 3348 cm−1 band are due to OH− anions, a group from the residual H2O adsorbed on the surface of NBG [22–26]. These results confirm the presence of all the typical groups.
Bioactivity: Mechanisms
2017, Comprehensive Biomaterials IIS53P4 bioactive glass
2017, Management of Periprosthetic Joint Infections (PJIs)Mechanical behaviour of Bioactive Glass granules and morselized cancellous bone allograft in load bearing defects
2016, Journal of BiomechanicsCitation Excerpt :This surface makes the glass osteoconductive, with very strong bonds to bone being formed in vivo (Andersson et al., 1990a; Andersson and Kangasniemi, 1991; Andersson et al., 1992; Heikkila et al., 1993, 1995). Additionally, the physicochemical reactions lead to a series of interactions that stimulate new bone formation (Gough et al., 2004b, 2004a; Loty et al., 2001; Matsuda and Davies, 1987; Vrouwenvelder et al., 1993; Vrouwenvelder et al., 1992; Waselau et al., 2012; Xynos et al., 2001, 2000b, 2000a; Zhou et al., 2010). Because of the aforementioned advantageous properties, BAG is currently used for various clinical indications.
HAp granules encapsulated oxidized alginate-gelatin-biphasic calcium phosphate hydrogel for bone regeneration
2015, International Journal of Biological MacromoleculesCitation Excerpt :A bonding mechanism between bone and bioactive ceramics has been reported for bioactive glass, glass–ceramics, and calcium phosphate based materials such as HAp [69,70]. It is well known that proteins have the ability to create bond to the apatite crystal surface of the ceramic [71]. So apatite formation is a crucial feature in bone formation.
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Visiting Research Fellow. Permanent address: Department of Orthodontics, University of Kagoshima Dental School, Usuki-cho, Kagoshima, 890 Japan.