Hormonal regulation of complement biosynthesis in human cell lines—I. Androgens and gamma-interferon stimulate the biosynthesis and gene expression of C1 inhibitor in human cell lines U937 and HepG2
References (28)
- et al.
A biochemical abnormality in hereditary angioneurotic edema: absence of serum inhibitor of Cl' esterase
Am. J. Med.
(1963) - et al.
Molecular cloning of human Cl inhibitor: sequence homologies with α 1-antitrypsin and other members of serpins superfamily
Gene
(1986) - et al.
Danazol for the treatment of idiopathic thrombocytopenic purpura
New Engl. J. Med.
(1983) - et al.
Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA
Eur. J. Biochem.
(1980) - et al.
Biosynthesis of complement subcomponents Clq, Clr, Cls and Cl inhibitor by resting and stimulated human monocytes
Biochem. J.
(1982) - et al.
Control of expression of MHC-linked C4 and Slp proteins by nonMHC genes
- et al.
Molecular basis for the deficiency of complement 1 inhibitor in type I hereditary angioneurotic edema
J. clin. Invest.
(1987) Hereditary angioneurotic edema, 1887–1987
New Engl. J. Med.
(1987)- et al.
Hormonal regulation of complement biosynthesis in human cell lines—II. Up-regulation of the biosynthesis of complement components C3, factor B and Cl inhibitor by interleukin-6 and interleukin-1 in human hepatoma cell line
Motec. Immun.
(1989,[object Object]) - et al.
Stimulation of histamine receptors of human monocytoid and hepatoma-derived cell lines as well as mouse hepatocytes modulates the production of the complement compents C3, C4, factor B and C2
Scand. J. Immun.
(1989,[object Object])
Treatment of hereditary angioedema with danazol
New Engl. J. Med.
(1976)
Human C1 inhibitor: improved isolation and preliminary structural characterization
Biochemistry
(1983)
Inhibition of the complement activation by an adrenal androgen, dehydroepiandrosterone
Complement
(1984)
Cl-inhibitor: evidence for decreased hepatic synthesis in hereditary angioneurotic oedema
Science
(1971)
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Inherited Complement Deficiencies
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2018, Vitamins and HormonesCitation Excerpt :DHEA may play a role in innate immunity via regulation of parts of the complement cascade. In vitro experimentation suggests that DHEA increases the expression of C1 inhibitor, a protein that inhibits activation of the complement cascade (Falus et al., 1990; Hidvégi, Fehér, Feher, Koó, & Füst, 1984; McLachlan et al., 1996). However, as concentrations used in in vitro studies may not reflect natural physiology in vivo, and studies such as live subject supplementation have not been conducted, it can be difficult to interpret these findings.
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