Original paperAggressive fibromatosis: optimisation of local management with a retrospective failure analysis
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The management of desmoid tumours: A joint global consensus-based guideline approach for adult and paediatric patients
2020, European Journal of CancerResults of a phase ii pilot study of moderate dose radiotherapy for inoperable desmoid-Type fibromatosis-An EORTC STBSG and ROG study (EORTC 62991-22998)
2013, Annals of OncologyCitation Excerpt :Retrospective data from several published series support the role of postoperative radiotherapy in preventing progression or reducing the incidence of local recurrence in case of recurrent tumors or resected tumors with involved surgical margins [7–9]. Radiotherapy alone as a treatment modality for this disease has been used in a few series of limited size [8, 10, 11]. In these series, the authors report slow regression and prolonged progression-free interval.
Limb salvage surgery in the excision of a massive fibromatosis
2011, Annals of Thoracic SurgeryCitation Excerpt :However, the rarity of fibromatosis precludes large clinical trials to allow conclusive data on treatment other than surgery. Salvage surgery for recurrence has been reported as successful, with amputations typically undertaken for either loss of limb function or pain [7]. Yet, in a setting in which radical excision is not known to improve disease-free survival, the loss of limb with its impact on quality of life is not necessarily justified, unless to alleviate symptoms, as this case implies.
Role of radiotherapy in the management of desmoid tumors
2011, International Journal of Radiation Oncology Biology PhysicsIntraoperative Electron Radiotherapy for the Management of Aggressive Fibromatosis
2010, International Journal of Radiation Oncology Biology PhysicsTreatment of Aggressive Fibromatosis: the Experience of a Single Institution
2009, Clinical OncologyCitation Excerpt :The treatment of fibromatosis usually consists of adequate surgery with a wide surgical margin (the definition of this margin is still contradictory), plus or minus postoperative radiotherapy [1,11,12]. Chemotherapy, non-steroidal anti-inflammatory drugs or tamoxifen have been used, with limited published data [13,14]. In case surgery is considered dangerous or devastating for the patient [15], radiotherapy can still be used preoperatively or as a single treatment modality [14].