Biochemical aspects of cell death
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Cited by (9)
Microbial DNA in human nucleic acid extracts: Recoverability of the microbiome in DNA extracts stored frozen long-term and its potential and ethical implications for forensic investigation
2022, Forensic Science International: GeneticsCitation Excerpt :After death, the physical and chemical barriers of the immune system that limit bacterial migration break down, facilitating movement of bacteria into nearby tissues [39]. Internal organs are normally considered to be sterile in healthy adults, but within 24 h postmortem, microbes start to proliferate [40]. Due to their persistent sterility for up to five days postmortem, the liver and pericardial fluids are therefore optimal sampling sites to evaluate the degree of postmortem microbial migration [41].
What is the "thanatomicrobiome" and what is its relevance to forensic investigations?
2018, Forensic Ecogenomics: The Application of Microbial Ecology Analyses in Forensic ContextsDistinctive thanatomicrobiome signatures found in the blood and internal organs of humans
2014, Journal of Microbiological MethodsCitation Excerpt :What happens to these microbial cells after a person dies is not well known. We do know that human cells become hypoxic because blood circulation ceases when the heart stops pumping (Gevers, 1975). Hypoxia triggers the release of intracellular factors that cause the organized degradation of cellular organelles by autolytic enzymes (Proskuryakov et al., 2003).
Thanatomicrobiome in forensic medicine
2023, New MicrobiologicaMicrobiome in Death and Beyond: Current Vistas and Future Trends
2021, Frontiers in Ecology and Evolution