Hormonal requirements for neuronal survival in culture
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Cited by (29)
Insulin, synaptic function, and opportunities for neuroprotection
2011, Progress in Molecular Biology and Translational ScienceCitation Excerpt :Furthermore, dramatically reducing IR density in the hypothalamic arcuate nucleus with antisense oligodeoxynucleotides191 precipitated an increase in feeding behavior, while the CNS-specific disruption of the IR gene led to both hyperphagia (in female mice) and increased body weight.192 The apparent peak of insulin binding and IR transcript expression in the part of the lifespan when brain development proceeds most rapidly,69,80,118,152,153,155,158,159 together with the unique ability of insulin to promote the growth of neurons maintained in a chemically defined medium,193–196 contributed to the view that the hormone had an important neurotrophic role. The most thoroughly examined effect of insulin on neural development has likely been in the area of neurite outgrowth.
A rapid fluorometric assay to measure neuronal survival in vitro
1993, Journal of Neuroscience MethodsEffect of glucocorticoids on development of the membrane resting potential of chick embryo brain cells in culture
1985, International Journal of Developmental Neuroscience