Prognostic significance of early cardiac index measurements in severely burned patients
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Effect of comorbidities on clinical outcome of patients with burn injury — An analysis of the German Burn Registry
2021, BurnsCitation Excerpt :A significant effect of peripheral arterial disease (OR 1.37 [0.80–2.20], p = 0.151) and/or heart insufficiency (OR 1.81 [0.97–3.41], p = 0.064) on mortality was not detected in our study cohort. This finding is interesting as cardiovascular diseases (CVDs) on the one side are the leading causes of death worldwide [23,24] and on the other side the pathophysiological mechanisms of “burn shock” also involving the vascular system, due to increased microvascular permeability, vasodilation and increased extravascular osmotic activity have been shown to lead to a considerably higher rate of complications [16,25–28]. Nevertheless, our results implicate a certain influence of pre-existing arrhythmias, as a significantly higher number of surgeries were needed those patients.
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