International Journal of Radiation Oncology*Biology*Physics
Original contributionCancer of the urinary bladder category t2, t3, (NXM0) treated by interstitial radium implant: Second report
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Cited by (58)
Brachytherapy after external beam radiotherapy and limited surgery preserves bladders for patients with solitary pT1-pT3 bladder tumors
2012, Annals of OncologyCitation Excerpt :The tumor located in the bladder neck is a relative contra-indication for implantation as this area is not easily accessible for implant materials. This technique was first described by Breur et al. in 1956 and propagated by Van der Werf-Messing in the 1970s and 1980s [13–15]. About half of the radiation oncology departments in the Netherlands and a few centers in France and Belgium followed this technique [16–25].
Defining the Clinical Target Volume for Bladder Cancer Radiotherapy Treatment Planning
2009, International Journal of Radiation Oncology Biology PhysicsCitation Excerpt :However, despite these recent advances, there still remain the ∼30% of patients who either fail to attain a complete response or subsequently develop a local relapse in the bladder (2). It is noteworthy that up to 95% of recurrences occur at the original site of disease (11). The International Commission on Radiation Units and Measurements (ICRU) Report 50 has provided a conceptual framework for 3D-CRT to ensure adequate coverage of the tumor with the prescription dose (12).
Results of Bladder-Conserving Treatment, Consisting of Brachytherapy Combined With Limited Surgery and External Beam Radiotherapy, for Patients With Solitary T1-T3 Bladder Tumors Less Than 5 cm in Diameter
2007, International Journal of Radiation Oncology Biology PhysicsRadiotherapy for Bladder Cancer
2007, UrologyCitation Excerpt :Interstitial radiation, as an alternative to external-beam treatment, allows a high dose of radiation to be delivered focally to a small area of the bladder with relative sparing of surrounding normal tissues. It has been used to treat selected, otherwise well patients with solitary tumors that are <5 cm in diameter and preferably confined to the bladder wall (pT1 or pT2).21–26 The broadest experience to date with interstitial radiotherapy for bladder cancer, described by Rozan et al.,25 was based on the study of 205 patients treated at 8 radiotherapy centers in France.
Radiation therapy for muscle-invasive bladder cancer: Treatment planning and delivery
2005, Clinical OncologyCitation Excerpt :Partial bladder treatments have been explored, fuelled by the knowledge that partial bladder-radiation tolerance is higher than the whole organ, with tolerance doses estimated at 80 Gy for two out of three of the bladders, and indeed higher for lesser volumes compared with 65 Gy for the whole organ [17,18]. Patterns of failure elucidated from the Dutch brachytherapy experience show that only 5–7% of patients develop recurrence at new sites within the bladder after brachytherapy implantation [19]. These data suggest that delivering treatment to the tumour (with margin) may be an alternative strategy.
Radiation therapy for muscle-invasive bladder cancer: Treatment planning and delivery in the 21st century
2005, Seminars in Radiation Oncology