Neuropeptide Y immunoreactivity in the hamster geniculo-suprachiasmatic tract
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Distinct feedback actions of behavioural arousal to the master circadian clock in nocturnal and diurnal mammals
2021, Neuroscience and Biobehavioral ReviewsCitation Excerpt :Considering our results in the diurnal grass rat, it could be interesting to test whether caffeine consumption in humans may not potentiate the shifting effects of light exposure with lower intensities. The SCN afferents involved in the non-photic modulation of circadian rhythms have been divided into two major pathways: 1) the GHT originating in the IGL, which contains NPY and GABA amongst others (Harrington et al., 1985; Moore and Card, 1994), and 2) an ascending serotonergic pathway originating in the median raphe nucleus (Meyer-Bernstein and Morin, 1996) (Fig. 3). Emerging evidence also relates other neurochemical (e.g. cholinergic and orexinergic) pathways to the non-photic regulatory mechanisms of circadian phase (Webb et al., 2008; Yamakawa et al., 2016).
Orchestration of the Circadian Clock Network by the Suprachiasmatic Nucleus
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2010, Molecular and Cellular ProteomicsCitation Excerpt :The observation of the unique peptide in the present study could indicate that the AA 111–128 fragment has some functional role, that PACAP is synthesized in the SCN, or that there is local translation of PACAP mRNA into its prohormone. Neuropeptide Y and γ-aminobutyric acid (GABA) are putative transmitters of non-photic signals via the geniculohypothalamic tract to the SCN (77–91). We observed C-flanking peptide of neuropeptide Y, which was reported in geniculohypothalamic tract projections to the SCN (82), and the peptide fragment of GABA receptor subunit α-6.
Cannabinoids and hamster circadian activity rhythms
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