Case ReportsAngiosarcoma at the site of a Dacron vascular prosthesis: A case report and literature review*
Section snippets
Case report
A 56-year-old white man underwent an uneventful repair of an infrarenal aortic aneurysm on Feb. 7, 1986, with placement of a bifurcated woven double-velour Dacron graft.
In late August 1989 he began to complain of left lower quadrant and lower back pain with sciatica. In September after radiologic examination of the lumbar spine was nondiagnostic for degenerative disk disease, a differential diagnosis including diverticular disease and pseudoaneurysm led to CT scanning of the abdomen because his
Discussion
After the description of Voorhees et al.6 of arterial replacement using flexible tubes of synthetic “Vinyon N” in 1951, the next 5 years saw the investigation of Teflon, Dacron, and Orlon as potential arterial substitutes.7
While carrying out studies on hypertension in 1948, Oppenheimer et al.8 noted that rat kidneys wrapped in cellophane caused sarcomas. Further studies in murine species have shown that plastic films embedded subcutaneously can induce malignant mesenchymal tumors in 7% to 50%
References (13)
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Angiosarcoma of the aorta associated with a Dacron graft
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(1981) - et al.
Sarcoma associated with Dacron prosthetic material
J Thorac Cardiovasc Surg
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Risk assessment of carcinogenesis at implantation sites
Plast Reconstr Surg
(1980) - et al.
Primary sarcoma of the aorta associated with a vascular prosthesis. A case report
Cancer
(1980) - et al.
Fibrosarcoma occurring at the site of a plastic vascular graft
Cancer
(1972) - et al.
Use of tubes constructed from Vingon “N” cloth in bridging arterial defects
Ann Surg
(1952)
Cited by (91)
Rare tumors: Angiosarcoma
2023, Bulletin du CancerPleomorphic undifferentiated aortic sarcoma presenting as persistent endoleak after endovascular aneurysm repair
2019, Journal of Vascular Surgery Cases and Innovative TechniquesPopliteal Angiosarcoma after Bypass with Autologous Saphenous Vein
2019, Annals of Vascular SurgeryEpithelioid angiosarcoma revealed by livedoid distal vascular emboli
2018, Human Pathology: Case ReportsAortic Epithelioid Angiosarcoma after Endovascular Aneurysm Repair
2016, Annals of Vascular Surgery
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