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Seroepidemiology and virology of HTLV-1 in the city of Mashhad, northeastern Iran

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Abstract

A serological survey of human T-cell lymphotropic virus type 1 (HTLV-1) antibodies was undertaken when sporadic cases of adult T-cell leukaemia were reported from Mashhad in northeastern Iran. Our findings in this study indicate that 35 of the 1511 serum samples were positive (2.3%) and the polymerase chain reaction (PCR) study showed that the virus which originated in Mashhad is classical HTLV-1 belonging to the cosmopolitan molecular group.

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