Original articleDetection of squamous cell cancer and pre-cancerous lesions by imaging of tissue autofluorescence in the hamster cheek pouch model
References (30)
- et al.
Early detection of lung cancer by means of hematoporphyrin derivative fluorescence and laser photoradiation
Clin Chest Med
(1985) - et al.
Detection of early lung cancer using low dose photophrin II
Chest
(1990) - et al.
Tumour localizing and photosensitizing properties of hematoporphyrin derivative in hamster buccal pouch carcinoma
Oral Surg Oral Med Oral Pathol
(1986) Autofluorescence of bovine ligamentum nuchae, cartilage, heart valve and lung measured by microscopy and fibre optics
Res Veterinary Science
(1988)- et al.
Argon ion laser-induced autofluorescence in normal and atherosclerotic aorta and coronary arteries: morphologic studies
Am Heart J
(1989) - et al.
Detection and localization of early lung cancer by imaging techniques
Chest
(1991) Canadian Cancer Statistics 1990
(1990)- et al.
Cancer Statistics, 1991
CA
(1991) - et al.
Cancer of the head and neck
- et al.
The association of alcohol and tobacco with cancer of the mouth and pharynx
Am J Public Health
(1965)
Oral precancerous lesions
Hematoporphyrin derivative: a new aid for endoscopic detection of malignant tissue
J Thorac Cardiovasc Surg
Laser fluorescence bronchoscope for localization of occult lung tumours
Med Phys
Fluorometer for endoscopic diagnosis of tumours
Med Phys
Ratioing fluorometer probe for localizing carcinoma in situ in bronchi of the lung
Photochem Photobiol
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Fluorescence spectroscopy and imaging to improve diagnosis of normal and tumoral cytological pancreatic cells
2013, Pathology Research and PracticeCitation Excerpt :Autofluorescence of cells is produced by endogenous molecules that naturally occur in cells after excitation with a suitable wavelength. The presence of disease changes the concentration of the endogenous molecules, as well as the light scattering and absorption properties of the tissue or the cells, due to changes in a.o. blood concentration, nuclear size distribution, collagen content and epithelial thickness [28–31,9,32]. Therefore, the activation of the endogenous molecules (NAD(P)H, porphyrins) is necessary to improve the discrimination between normal and pancreatic tumor cells.
Color auto-fluorescence from cancer lesions: Improved detection of central type lung cancer
2007, Lung CancerCitation Excerpt :Fluorescence of red spectra has been observed in malignant tumors in animal models [26] as well as human oral and colon cancer [27,28]. Kluftinger et al. [29] reported that the R/G ratio of fluorescence from areas with squamous cell cancer was significantly higher than that from areas with squamous dysplasia in a hamster cheek pouch model. Kusunoki et al. [13] suggested that analyses of signal intensity based on the frequency of fluorescence acquired by the LIFE lung system might improve the detection rate of early lung cancer.
Biophotonic and other physical methods for characterizing oral mucosa
2005, Otolaryngologic Clinics of North AmericaCitation Excerpt :This profile depends sensitively on the molecular environment (eg, whether a protein is in its normally folded state or if a molecule is attached to a substrate). Autofluorescence has proven to be an effective discriminator of tissue health in the oral mucosa [9–11,16,64–94]. In particular, malignant transformation is thought to bring about alterations in the oxidative state and in the abundance of coenzymes NADH and FAD, degradation of collagen matrices, and changes in heme metabolism, thus changing the overall fluorescent characteristics of suspected tissue.
Characterization of autofluorescence in oral squamous cell carcinoma
2003, Oral OncologySteady-state fluorescence imaging of neoplasia
2003, Methods in EnzymologyAnalysis of fluorescence in oral squamous cell carcinoma
2002, Oral Oncology