Original articleK-ras gene mutations in adenomas and carcinomas of the colon
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Cited by (50)
Tumor-infiltrating lymphocytes and dendritic cells in human colorectal cancer: Their relationship to KRAS mutational status and disease recurrence
2011, Human ImmunologyCitation Excerpt :It has been reported that KRAS mutations occur early in colorectal carcinogenesis, often before the development of polyps [3,17,18]. The percentage of CRC patients with mutations in KRAS varies from 30 to 50%, most likely depending on the different techniques used for detection [7–9]. In our cohort of patients, we identified KRAS mutations in 45.5% of tumors, including 65% in codon 12 and 35% in codon 13, which agrees with previous studies [9,10].
Sensitive detection of KRAS mutations in archived formalin-fixed paraffin-embedded tissue using mutant-enriched PCR and reverse-hybridization
2009, Journal of Molecular DiagnosticsCopy number variation and rearrangements assessment in cancer: Comparison of droplet digital pcr with the current approaches
2021, International Journal of Molecular Sciences
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Present address: Department of Surgery, University of Liverpool, UK.
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