An ontogenetic theory for the explanation of congenital malformations involving the truncus and conus

Summaryo

1. A review of the classical concepts about the development and partitioning of the truncus-conus and the formation of the membranous ventricular septum of the human heart is made.

2. An ontogenetic theory is proposed to explain congenital truncoconal malformations. This theory is based upon the work of Davis, Streeter, and Kramer, as well as on the study of pathologic specimens from the Instituto Nacional de Cardiología of México, and from medical literature.

3. Our ontogenetic theory considers truncoconal congenital malformations as a consequence of developmental alterations of the conoventricular flange, the truncoconal ridges, and the primordia of the aortic and pulmonary cusps.

4. Old concepts are re-evaluated and new ones are established in relation to lateral positions, transposition, unequal partitioning at the expense of the aorta or pulmonary artery, common truncus, and valvular defects.

5. Anatomic and embryologic correlations are made in order to permit the pathologic diagnosis of these malformations.

6. The different pictures of isolated and combined trucoconal malformations (which actually exist or may theoretically exist according to the proposed theory) are described.

7. More common congenital truncoconal malformations are interpreted according to this theory: common truncus, Eisenmenger's complex, Fallot's tetralogy, truncus solitarius aorticus, transposition of the great vessels, and the Taussig-Bing complex.

Summario in Interlinguao

1. Es presentate un revista del conceptos classic in re le disveloppamento e le partition de trunco e cono e in re le formation del membranose septo ventricular del corde human.

2. Es proponite un theoria ontogenetic pro explicar congenite malformationes thrunco-conal. Iste theoria es basate super le labores de Davis, Streeter, e Kramer como etiam super le studio de specimens pathologic ab le Instituto National de Cardiologia de Mexico e ab le litteratura medical.

3. Nostre theoria ontogenetic considera congenite malformationes truncoconal como consequentia de alterationes disveloppamental del collar conoventricular, del crestas trunco-conal, e del primordios del cuspides aortic e pulmonar.

4. Conceptos traditional es re-evalutate e nove conceptos es establite in re positiones lateral, transposition, e partition inequal al expensa de aorta o arteria pulmonar, trunco commun, e defectos valvular.

5. Correlationes anatomic e embryologic es facite pro permitter le diagnose pathologic de iste malformationes.

6. Es describite le differente aspectos de isolate e combinate malformationes trunco-conal (le quales existe de facto o pote exister theoricamente de accordo con le theoria proponite).

7. Le plus commun congenite malformationes trunco-conal es interpretate de accordo con nostre theoria. Le malformationes assi interpretate include trunco commun, complexo de Eisenmenger, tetralogia de Fallot, trunco solitari aortic, transposition del grande vasos, e le complexo de Taussig-Bing.