Effects of bisoprolol on heart rate variability in heart failure
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2019, British Journal of AnaesthesiaCitation Excerpt :Application of our analysis revealed reductions in HF specific to myocardial injury strongly suggesting involvement of a parasympathetic component19 that may otherwise not have been revealed with the conventional parameters. The confounding influences of co-morbidities38,39 and cardiac medications40 are potential limitations. However, the design of the study mitigated potential confounding factors, as each patient served as their own control.
Targeting the autonomic nervous system: Measuring autonomic function and novel devices for heart failure management
2013, International Journal of CardiologyCitation Excerpt :A SDNN of between 50 and 100 ms was related to an annual mortality of 12.7% compared to a mortality of 5.5% in patients with a SDNN > 100 ms [31]. The HRV sub-study of CIBIS (Cardiac Insufficiency BIsoprolol Study) showed that β-blockers improve HRV and in particular those markers that reflect the PNS [32]. Unfortunately, many of these trials are from the 1990s and their findings in patients with ischaemic cardiomyopathy may not be directly transferable in the contemporary era of revascularisation.
Heart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction
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