Original articleAqueous shunt devices compared with trabeculectomy with Mitomycin-C for children in the first two years of life☆
Section snippets
Methods
A retrospective review of medical records identified all patients 24 months of age or younger who underwent aqueous shunt implantation by two surgeons (A.D.B. and S.F.F.) at their respective institutions from August 1994 to October 2001. Follow-up for these patients is reported through July 2002. Institutional review board approval was obtained for data review and analysis. The cohort receiving an aqueous shunt device was compared with an age-matched cohort of patients receiving MMC
Results
Forty-six eyes of 32 patients were identified that underwent aqueous shunt implantation before 25 months of age. Twenty-four eyes of 19 patients that underwent mitomycin trabeculectomy in this same age group were used for comparison. Table 1 summarizes the demographics of these two groups. Statistical analyses of the two groups were not significant for age at surgery, prior surgeries, or diagnostic groups. There was a trend for more aphakic eyes in the aqueous shunt group of borderline
Discussion
The efficacy and safety of aqueous shunt devices and trabeculectomy with adjunctive MMC for glaucomas occurring in childhood have been established in previous studies.4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20 However, pediatric glaucomas are much less common than adult-onset glaucoma and are representative of a much wider spectrum of pathology. Wide variation in treatment may be recommended by centers experienced in the treatment of pediatric glaucoma. Randomized, prospective
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This work was supported, in part, by an unrestricted grant from Research to Prevent Blindness, New York, New York, and by an NEI Departmental Core Grant (P30 EY06360).