Ultrasound biomicroscopy of ciliary body cysts

doi:10.1016/S0002-9394(98)00308-0

American Journal of Ophthalmology

Volume 127, Issue 1, January 1999, Pages 48-55

https://doi.org/10.1016/S0002-9394(98)00308-0 Get rights and content

Abstract

PURPOSE: To report the incidence and sector distribution of ciliary body cysts in normal subjects and to assess association with age using ultrasound biomicroscopy.

METHODS: We prospectively examined 232 eyes of 116 normal subjects (51 men and 65 women) ranging in age from 15 to 84 years (mean ± SD, 45.2 ± 20.1). Complete ophthalmic examination, including gonioscopy and ophthalmoscopy with mydriasis, was performed. In addition, the circumference of the ciliary body was divided into eight sectors, and scanned in transverse and radial sections by high-resolution ultrasound biomicroscope to determine the incidence, distribution, and location of cysts.

RESULTS: Based on one randomly chosen eye from each subject, cysts were detected in 63 (54.3%) of the 116 subjects. Cysts were found most frequently and in greater numbers in the inferior and temporal sectors. The incidence and the distribution range, expressed as the number of involved sectors per eye, were 73.1% and 3.8, respectively, for subjects 20 ∼ 29 years old; both incidence and the number of involved sectors decreased with age (P = .0001). Cyst diameter ranged from 200 to 2500 μm; mean size decreased with age (P = .001). Gender and refractive error did not affect the incidence and distribution. There was significant bilateral correlation in the number, incidence, and distribution of ciliary body cysts.

CONCLUSION: Ultrasound biomicroscopy disclosed a high incidence of ciliary body cysts in normal subjects, which decreased with age. Cysts were multiple and bilateral in many subjects.

Section snippets

Subjects and methods

In this prospective study, 232 eyes of 116 normal subjects (51 men and 65 women) were examined. Thirty-five of 116 normal subjects were healthy volunteers, and 81 were eye clinic patients. Both eyes were examined in all 116 subjects. Subjects’ ages ranged from 15 to 84 years (45.2 ± 20.1, mean ± SD). Complete ophthalmic examinations included slit lamp, gonioscopy, and ophthalmoscopy. Gonioscopic examination was done after mydriasis with one drop of 0.4% tropicamide (Mydrin M; Santen

Results

Gonioscopic examination after mydriasis revealed ciliary body cysts in two subjects at the time of initial screening. The gonioscopic findings obtained in these cases were compared with ultrasound biomicroscopic images of the same eye.

Discussion

High-frequency, high-resolution ultrasound bio-microscopy is a noninvasive technique that enables detection of anatomical aberrations of the iris and ciliary body. We used this technique to successfully detect ciliary body cysts, which are otherwise difficult to identify on routine clinical examination with slit lamp, gonioscopy, or indentation ophthalmoscopy.

Ultrasound biomicroscopy has a resolution of 40 μm, detecting cysts as small as 200 μm in diameter in our study. A combination of

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Original ArticlesUltrasound biomicroscopy of ciliary body cysts

Abstract

Section snippets

Subjects and methods

Results

Discussion

Am J Ophthalmol

Ophthalmology

Ophthalmology

Ophthalmology

Ophthalmology

Am J Ophthalmol

Am J Ophthalmol

Original Articles
Ultrasound biomicroscopy of ciliary body cysts