Original article: general thoracicOperation for lung cancer in patients with idiopathic pulmonary fibrosis: surgical contraindication?
Section snippets
Material and methods
From January 1992 through December 2001, 64 patients with simultaneous lung cancer and IPF were seen at the Respiratory Diseases Center, Kyoto-Katsura Hospital, and their records were analyzed in the present study. The three entry criteria were as follows: lung cancer was discovered during follow-up for a past case of IPF or was discovered simultaneously with IPF; the diagnosis of lung cancer was confirmed either histologically or cytologically; and the diagnosis of IPF was confirmed as will be
Results
The group of 64 patients comprised 56 men and 8 women with an average age of 68.8 years (range, 43 to 85 years).
Comment
This is one of the first reports compiling the surgical results for patients with concomitant UIP or IPF and lung cancer. Our study showed a poor prognosis for these patients even after complete resection of the lung cancer, with 2- and 5-year survival rates of 52% and 0%, respectively. The question of whether to operate is under debate, as patients with IPF are known to have a poor prognosis, and those with unresected lung cancer have a terrible course. We should consider not only whether to
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