Main articleRapid eye movements density as a measure of sleep need: REM density decreases linearly with the reduction of prior sleep duration
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2020, Neuroscience and Biobehavioral ReviewsCitation Excerpt :Notably, increased REM density was also observed in high-risk individuals, suggesting this alteration may precede the onset of the disease. Some authors suggested that REM density can be used as a measure of sleep need, with a higher density associated with a reduction in sleep need in healthy subjects (Lucidi et al., 1996). Moreover, using a forced desynchrony protocol, which is capable of distinguishing sleep- and circadian-dependent modulation, Khalsa et al. (2002) found that REM density is not related to circadian rhythm, but it changes as a function of sleep time.
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2020, Sleep Medicine ReviewsEffects of acute physical exercise in the light phase of sleep in rats with temporal lobe epilepsy
2017, Epilepsy ResearchCitation Excerpt :Studies investigatating how neurotransmitters are affected by the epileptic condition during exercise are warranted to elucidate this topic. Some authors argued that these positive changes are linked to changes in body temperature (Diekelmann and Born, 2010; Kline, 2014; Kubitz et al., 1996; Lucidi et al., 1996; Peigneux et al., 2004; Uchida et al., 2012; Walker and van der Helm, 2009; Youngstedt, 2005), cytokine concentrations (Santos et al., 2007), metabolic rate (Morselli et al., 2012; Uchida et al., 2012) and secretion of growth hormones and neurotrophins (Zagaar et al., 2013). Sleep duration and the amount of SWS may increase as a function of wakefulness and energy expenditure (Berger and Phillips, 1988).