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Maternal serum dioxin-like activity and gestational age at birth and indices of foetal growth: The Aarhus birth cohort
2023, Science of the Total EnvironmentPCBs
2019, Encyclopedia of Environmental HealthEffects of Environmental Exposures on Fetal and Childhood Growth Trajectories
2016, Annals of Global HealthCitation Excerpt :Although occupationally174,175 and accidentally poisoned women176,177 have showed an increased risk for giving birth to LBW infants, studies of prenatal low- level exposure to PCBs and LBW have produced inconsistent results (Table 3). In particular, 7 studies evaluating exposure to low levels of PCBs in relation to LBW have supported an increased risk,155-158,175,178,179 whereas 5 other studies showed no relationship,160-164 and 2 other studies showed that increased exposure was associated with having heavier babies.159,180 One study158 assessed 76 PCB congeners in maternal serum from 52 US women and found an inverse association between PCB exposure and birth weight, and also provided 3 important observations:
Maternal exposure to brominated flame retardants and infant Apgar scores
2015, ChemosphereCitation Excerpt :However, a study of women who were exposed to PBB in utero suggested that those with higher exposures during this critical window had increased odds of spontaneous abortion when they reached adulthood and became pregnant, compared to those with the lowest exposure (Small et al., 2011). For PCB, some human studies have found statistically significant associations with spontaneous abortion (Bercovici et al., 1983; Leoni et al., 1989), while others have not (Dar et al., 1992; Axmon et al., 2004). There was a suggested, although not statistically significant, increase in stillbirth among women in the Yucheng cohort, who were exposed to high levels of PCB through contaminated cooking oil (Yu et al., 2000).
Growth in Inuit children exposed to polychlorinated biphenyls and lead during fetal development and childhood
2014, Environmental ResearchCitation Excerpt :Since those incidents, several studies conducted with populations exposed to background PCB levels have been undertaken to examine the associations between in utero exposure and fetal growth. However, inconsistent results have been reported with regard to prenatal PCB exposure in populations with lower exposure: eight studies reported significant associations with lower birth weight (Fein et al., 1984, Dar et al., 1992, Patandin et al., 1998, Rylander et al., 1998, Karmaus and Zhu, 2004, Lamb et al., 2006, Sonneborn et al., 2008, Murphy et al., 2010, Wojtyniak et al., 2010), while nine others failed to detect significant associations with neonate growth (Rogan et al., 1987, Vartiainen et al., 1998, Grandjean et al., 2001, Gladen et al., 2003, Longnecker et al., 2005, Givens et al., 2007, Khanjani and Sim, 2007, Sagiv et al., 2007, Wolff et al., 2007). Recently, a meta-analysis involving 12 European birth cohorts concluded that birth weight was reduced in relation with cord PCB 153 concentrations (Govarts et al., 2010).