Elsevier

Fertility and Sterility

Volume 48, Issue 5, November 1987, Pages 783-786
Fertility and Sterility

Gynecology-endocrinology
Cervical mucus changes in relationship to urinary luteinizing hormone*

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In order to evaluate the relationship between the urinary luteinizing hormone (LH) surge as detected by the OvuSTICK (Monoclonal Antibodies, Inc., Mountain View, CA) method and daily cervical mucus parameters, ten spontaneously ovulating women undergoing infertility evaluation were followed during their cycles with twice daily urinary LH testing as well as daily ultrasound, mucus evaluation, and hormonal assays of serum LH, progesterone (P), and estradiol (E2). Maximal cervical mucus scores, as determined using a modified Insler score, were noted to coincide consistently with the urinary LH surge as detected by twice daily testing and to precede ultrasound evidence of ovulation by 0 to 24 hours. Mucus scores rapidly declined in the 24-hour period following the urinary LH surge. Detection of the urinary LH surge may therefore help identify that period of time during which cervical mucus parameters are optimal and therefore facilitate the timing of artificial insemination, intercourse, or postcoital testing.

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*

Presented at the forty-second annual meeting of The American Fertility Society and the eighteenth annual meeting of the Canadian Fertility and Andrology Society, September 27 to October 2, 1986, Toronto, Ontario, Canada.

Present address: John Nulsen, M.D., Department of Obstetrics and Gynecology, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, Connecticut 06032.

Reprint requests: Luis Blasco, M.D., Professor, Department of Obstetrics and Gynecology, Suite 106 Dulles Building, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, Pennsylvania 19104.